Achieving the Goals of the Cancer Moonshot Requires Progress against All Cancers.

In February 2022, President Joseph R. Biden made reducing age-adjusted cancer mortality by at least 50% over the next 25 years a key goal of the Cancer Moonshot. Although recent progress puts this goal within reach, succeeding will require major commitments to progress on all fronts: basic research, clinical and translational research, health care delivery, and public health. See related article by Shiels et al., p. 1084 (2).