Background: Individuals with Down syndrome (DS) exhibit deficits in static and dynamic balance abilities and maladaptive functions. This study aimed to determine the effectiveness of dance movement therapy (DMT) group intervention in individuals with DS.
Methods: The 31 participating individuals with DS, aged 5-29 years, were randomly divided into intervention (n = 16) and control (n = 15) groups. Posturography was used for static balance measurement, timed up and go test for dynamic balance measurement and the Achenbach System of Empirically Based Assessment (ASEBA) questionnaire for adaptive function and behavioural problem measurement in participants before and after the DMT interventions. The intervention group underwent 60-min DMT intervention once a week for 10 times, while the control group had usual daily activities.
Results: The results revealed a statistically significant difference and large effect sizes in dynamic balance [(f(1, 29) = 4.52, P = 0.04, η = 0.14)] in the intervention group compared with the control group. There were no statistically significant differences in static balance and ASEBA scores between the groups.
Conclusions: This study found that the DMT interventions helped to improve the dynamic balance in individuals with DS.
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http://dx.doi.org/10.1111/jir.13033 | DOI Listing |
Proc Natl Acad Sci U S A
February 2025
Courant Institute for Mathematical Sciences and Department of Biology, New York University, New York, NY 10012.
Accurate chromosome segregation in mitosis depends on proper connections of sister chromatids, through microtubules, to the opposite poles of the early mitotic spindle. Transiently, many inaccurate connections are formed and rapidly corrected throughout the mitotic stages, but a small number of merotelic connections, in which a chromatid is connected to both spindle poles, remain lagging at the spindle's equator in anaphase. Most of the lagging chromatids are eventually moved to one or the other pole, likely by a combination of microtubules' turnover and the brute force of pulling by the microtubules' majority from the one pole against the microtubules' minority from the other pole.
View Article and Find Full Text PDFPLoS Pathog
January 2025
Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET). Córdoba, Argentina.
Tissue-repair regulatory T cells (trTregs) comprise a specialized cell subset essential for tissue homeostasis and repair. While well-studied in sterile injury models, their role in infection-induced tissue damage and antimicrobial immunity is less understood. We investigated trTreg dynamics during acute Trypanosoma cruzi infection, marked by extensive tissue damage and strong CD8+ immunity.
View Article and Find Full Text PDFChaos
January 2025
Institut de Neurosciences des Systèmes, Aix-Marseille University, INSERM, Marseille 13005, France.
ACS Nano
January 2025
Department of Mechanical Engineering, The University of Hong Kong, Hong Kong, China.
Structured surfaces leverage interfacial energy for directional liquid manipulation without external power, showing tremendous potential in microfluidics, green energy and biomedical applications. While the interplay of interfacial energy between solid surfaces and liquids is crucial for liquid manipulation, a systematic understanding of how the balance in liquid-solid interfacial energy affects liquid behaviors remains lacking. Here, using the curvature-ratchet surface as a generic example, we reveal the complex directional liquid dynamics inherent in the subtle regulation of liquid-solid interfacial energy.
View Article and Find Full Text PDFSci Rep
January 2025
Faculty of Social Sciences, University of Lodz, ul. Prez, prez. Gabriela Narutowicza 68, 90-136, Łódź, Poland.
Based on a balanced panel dataset of 272 prefecture-level cities from 2000 to 2022, this paper systematically investigates the impact of the carbon emissions trading system on green total factor productivity and its underlying mechanisms from an integrated perspective of overall, dynamic, and spatial dimensions. The findings reveal that (1) the carbon emissions trading system significantly enhances regional total factor productivity, primarily by optimizing resource allocation efficiency and strengthening regional competitiveness. (2) From a dynamic perspective, the policy effect exhibited a U-shaped relationship: from 2013 to 2018, green total factor productivity was suppressed due to underdeveloped market mechanisms and the policy environment; after 2018, with market maturation and policy stabilization, the policy effects improved significantly.
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