A 44-year-old female patient with multiple sclerosis (MS) treated with ocrelizumab was hospitalized with SARS-CoV-2 pneumonia three times over the course of five months, eventually expiring. Viral sequencing of samples from her first and last admissions suggests a single persistent SARS-CoV-2 infection. We hypothesize that her immunocompromised state, due to MS treatment with an immunosuppressive monoclonal antibody, prevented her from achieving viral clearance.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104259 | PMC |
| http://dx.doi.org/10.21203/rs.3.rs-2768759/v1 | DOI Listing |
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