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A Case of Drug-Resistant Myoclonus Improved by Only Slight Adjustment to the Hemodialysis Setting. | LitMetric

AI Article Synopsis

  • Myoclonus is a rare complication seen in patients with end-stage renal disease but can usually be improved with hemodialysis.
  • An 84-year-old male with chronic renal failure experienced worsening involuntary limb movements after starting hemodialysis, showing signs of myoclonus on tests.
  • The condition was diagnosed as subcortical-nonsegmental myoclonus, and adjusting the hemodialysis settings rather than medication helped alleviate the symptoms, indicating that treatment approaches for drug-resistant myoclonus may need to consider hemodialysis adjustments.

Article Abstract

Myoclonus, a rare complication in patients with end-stage renal disease, is typically ameliorated through hemodialysis. The present case concerns an 84-year-old male with chronic renal failure undergoing hemodialysis, presenting involuntary movements in his limbs, which gradually worsened from the initiation of hemodialysis without constant elevation of serum blood urea nitrogen and electrolytes levels. Surface electromyography revealed characteristic findings consistent with myoclonus. He was diagnosed with subcortical-nonsegmental myoclonus related to hemodialysis, and the myoclonus was significantly alleviated after slightly increasing the post-dialysis target weight even though drug treatment was ineffective. This case suggests that drug-resistant myoclonus in patients with renal failure may be improved by adjusting hemodialysis settings, even in cases of atypical dialysis disequilibrium syndrome.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098026PMC
http://dx.doi.org/10.7759/cureus.36104DOI Listing

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