An Al2014-alumina (AlO) composite's characteristics are significantly influenced by the reinforcement particle size variation. Therefore, this study examines the microstructure, mechanical, fractography, and wear performance of an Al2014-AlO composite made using a unique two-stage stir casting method and various alumina weight fractions (9, 12, and 15 wt %). Three categories of alumina particle size are used, i.e., fine particle size (FPS, 8 μm), intermediate particle size (IPS, 53 μm), and coarse particle size (CPS, 88 μm). The shapes of the composites were characterized using scanning electron microscopy. According to scanning electron microscopic analyses of the microstructure, the FPS dispersion was more uniform than IPS and CPS, whereas CPS causes agglomeration. Additionally, the studies show that the FPS composite outperformed CPS and IPS composites in terms of mechanical characteristics and wear performance. The fractography study shows conical and equiaxed dimple failure in the Al2014 matrix and the circular cavities.
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http://dx.doi.org/10.1021/acsomega.3c01163 | DOI Listing |
Nanoscale
January 2025
State Key Laboratory of Biobased Fiber Manufacturing Technology, Tianjin Key Laboratory of Pulp and Paper, China Light Industry Key Laboratory of Papermaking and Biorefinery, Tianjin University of Science and Technology, No. 29, 13th Street, TEDA, Tianjin 300457, P. R. China.
The remarkable catalytic activity, optical properties, and electrochemical behavior of nanomaterials based on noble metals (NM) are profoundly influenced by their physical characteristics, including particle size, morphology, and crystal structure. Effective regulation of these parameters necessitates a refined methodology. Lignin, a natural aromatic compound abundant in hydroxyl, carbonyl, carboxyl, and sulfonic acid groups, has emerged as an eco-friendly surfactant, reducing agent, and dispersant, offering the potential to precisely control the particle size and morphology of NM-based nanomaterials.
View Article and Find Full Text PDFNanotheranostics
January 2025
Department of Pathology and Laboratory Medicine, Warren Alpert Medical School, Brown University, Providence, RI 02912, USA.
In treating type 2 diabetes, avoiding glucose reabsorption (glucotoxicity) and managing hyperglycemia are also important. A metabolic condition known as diabetes (type-2) is characterized by high blood sugar levels in comparison to normal Bilosomes (BLs) containing Dapagliflozin (Dapa) were formulated, optimized, and tested for oral therapeutic efficacy in the current investigation. Used the Box Behnken design to optimize the Dapa-BLs, formulated via a thin-film hydration technique.
View Article and Find Full Text PDFFront Genet
December 2024
Department of Breast Surgery, General Surgery Center, First Hospital of Jilin University, Changchun, Jilin, China.
Objective: Previous studies have established a causal relationship between metabolites and breast cancer (BC), but the underlying mechanisms remain unclear. Thus, we aimed to investigate the genetic relationship between metabolites and BC, including its subtypes, using Mendelian randomization (MR) analysis.
Methods: Utilizing the latest and most comprehensive summary statistics from genome-wide association studies we conducted an Mendelian randomization study.
Small Methods
January 2025
Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
Rolling circle amplification (RCA)-derived ultra-long DNA is highly attractive and versatile because of its diverse functionalities conferred by repeated DNA nanostructures. However, magnesium pyrophosphate (MgPPi) crystals, as byproducts of RCA, electrostatically interact with the DNA to form DNA microhybrids and hamper its broad bioapplications, as its large size is unfavorable for cellular uptake and decreases the density of functional DNA nanostructures. In this study, finely tuned synthesis strategies are developed to condense the microhybrids and replace non-functional MgPPi crystals with various functional metal nanostructures by reducing metal ions.
View Article and Find Full Text PDFAnn Agric Environ Med
December 2024
School of Biomedical Engineering and Imaging, Hubei University of Science and Technology, Hubei, China.
Fungal contamination in the air of hospital wards can affect the health of medical staff, patients, and caregivers. Through systematic analysis of the concentration, types, and particle size distribution characteristics of fungi in the air of wards in Wuhan, China, in 2023, it was found that there was no significant correlation between the concentration of fungi in the air of wards and the disease type and personnel density. The main influencing factors were temperature, humidity, and seasonal changes.
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