Introduction: Natural orifice specimen extraction (NOSE) laparoscopic surgery is emerging as a new and promising technique, especially in gastric cancer (GC).

Aim: To analyze the difference between transvaginal and transumbilical specimen extraction following totally laparoscopic gastrectomy (TLG).

Material And Methods: Between January 2016 and July 2021, 37 consecutive female patients with GC who underwent either natural orifice specimen extraction surgery (NOSES) or TLG at our center were included and analyzed.

Results: In total, 12 patients underwent NOSES, and 25 patients underwent TLG. The NOSES group had a shorter operative time (239.3 ±21.5 vs. 256.1 ±21.2 min, p = 0.031) and shorter specimen extraction time (17.0 ±4.2 vs. 30.8 ±4.3 min, p < 0.01). No significant difference was observed in the comparison of the radical validity including estimated blood loss, the number of harvested LNs and the comparisons of distal and proximal margin. In the postoperative recovery comparisons, the NOSES group had a shorter time to first fluids (3.9 ±0.5 vs. 5.6 ±1.2 days, p < 0.01), and time to starting a soft diet (5.6 ±0.7 vs. 7.7 ±1.7 days, p < 0.01). Postoperative pain in the NOSES group was significantly less. Postoperative hospital stay days in the NOSES group were fewer (10.2 ±2.2 vs. 12.4 ±2.9 days, p = 0.030). Overall, the postoperative complications were similar between the two groups (p = 0.438). When more cases were included, the results were similar. NOSES reduced hospital costs for GC patients, and it also applied to the premenopausal patients.

Conclusions: NOSES was a safer and more reliable method as compared to transumbilical specimen extraction.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091923PMC
http://dx.doi.org/10.5114/wiitm.2022.119239DOI Listing

Publication Analysis

Top Keywords

specimen extraction
28
noses group
16
transumbilical specimen
12
patients underwent
12
extraction totally
8
totally laparoscopic
8
laparoscopic gastrectomy
8
female patients
8
gastric cancer
8
natural orifice
8

Similar Publications

Purpose: To create a computer-aided prediction (CAP) system to predict Wilms tumor (WT) responsiveness to preoperative chemotherapy (PC) using pre-therapy contrast-enhanced computed tomography (CECT).

Materials And Methods: A single-center database was reviewed for children <18 years diagnosed with WT and received PC between 2001 and 2021. Patients were excluded if pre- and post-PC CECT were not retrievable.

View Article and Find Full Text PDF

Background: Plasma biomarkers such as neurofilament light (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau‐181 (p‐tau‐181) have been thoroughly investigated in Alzheimer’s disease and other dementias. However, further investigations into how biological variables can influence biomarker concentrations in both normative and cognitively resilient populations will be important for more robust interpretations of biomarker levels. This study investigates how ageing modifies plasma biomarkers in a normative, epidemiologically representative Canadian population and in cognitively healthy seniors over 80 years old.

View Article and Find Full Text PDF

Aim: The aim of this study was to evaluate and compare the apical microleakage of zinc oxide (ZOE) eugenol and Endoflas as obturating materials using different root canal irrigants in primary teeth.

Materials And Methods: A total of 80 extracted primary anterior teeth were divided randomly into four groups with different irrigants and obturating materials used. Group I [ZOE + sodium hypochlorite (NaOCl)], group II [ZOE + NaOCI + ethylenediaminetetraacetic acid (EDTA)], group III (Endoflas FS + NaOCI), group IV (Endoflas FS + NaOCI + EDTA).

View Article and Find Full Text PDF

Too Far From Relatives? Impact of the Genetic Distance on the Success of Exon Capture in Phylogenomics.

Mol Ecol Resour

January 2025

Institut Systématique Evolution Biodiversité (ISYEB), Muséum National d'Histoire Naturelle, CNRS, EPHE, Sorbonne Université, Université Des Antilles, Paris, France.

The exon capture approach allows for sequencing a large number of loci to reconstruct phylogenetic relationships at varying taxonomic levels. In order to efficiently recover the targeted loci, the probes designed to capture the exons need to be genetically sufficiently similar to bind to the DNA, with a proposed limit of 10% of divergence. However, this threshold has never been tested with a specific protocol.

View Article and Find Full Text PDF

A new quantitative reverse transcription PCR assay to improve the routine diagnosis of paracoccidioidomycosis.

Med Mycol

January 2025

Mycology Department, National Reference Center for Invasive Mycoses and Antifungals, Translational Mycology Research Group, Institut Pasteur, Université Paris Cité, Paris, France.

Paracoccidioides are dimorphic fungal pathogens and the etiological agents of paracoccidioidomycosis (PCM). This severe systemic mycosis is restricted to Latin America, where it has been historically endemic. Currently, PCM presents the fewest diagnostic tools available when compared to other endemic mycoses.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!