AI Article Synopsis
- Bifunctional building blocks, like aryl glyoxal, have significant importance in synthetic chemistry due to their versatile applications.
- Aryl glyoxal is particularly valuable in creating various five- and six-membered heterocycles, which are essential components of many natural products.
- Recent advancements highlight the use of multicomponent reactions with aryl glyoxal to efficiently synthesize diverse oxygen heterocycles.
Article Abstract
The category of bifunctional building blocks overrides many others because of their fascinating wide applicability in synthetic chemistry. Aryl glyoxal is one of the key molecules that has been extensively used in heterocyclic chemistry to afford nearly all types of five- and six-membered heterocycles, which are the structural constituents of many natural products. The multicomponent reaction is a practical strategy to utilize this wonderful moiety with different types of starting materials to obtain numerous diverse oxygen heterocycles. This review covers the advancement of aryl glyoxal as a prime synthetic equivalent in recent years for the synthesis of oxygen heterocycles.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103687 | PMC |
| http://dx.doi.org/10.1039/d2ra08315a | DOI Listing |
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