Background: Identifying predictors of methamphetamine use can inform population prevention strategies.
Methods: Participants (n = 1265) born in Christchurch, New Zealand were followed from birth to age 40. Methamphetamine outcomes (any use since the last interview, and regular use, defined as any period of at least weekly use) were ascertained by self-report at six interviews from age 18 to 40. Predictors with plausible associations with methamphetamine use were extracted from the study database. These were grouped into early predictors (age 0-16), comprising childhood, familial and individual characteristics; and later time-dynamic correlates of methamphetamine use in adulthood (ages 16-40). Generalised estimating equation models were fitted to identify predictors of methamphetamine use outcomes.
Results: In adjusted models, paternal overprotectiveness and childhood anxious / withdrawn behavior were associated with any use of methamphetamine, but not regular use. Conversely, childhood conduct problems and parental illicit drug were associated with regular use but not any use. Male sex, high novelty seeking and deviant peer affiliations were associated with both any use and regular use in adjusted models. The strongest correlates of methamphetamine use in adulthood were unemployment, life stress and other substance use disorders (cannabis, nicotine, and alcohol).
Conclusion: Markers of externalizing problems in childhood and adolescence (conduct problems, high novelty seeking, parental illicit substance use, and deviant peer affiliations) are the strongest predictors of regular methamphetamine use in adulthood.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.addbeh.2023.107714 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Predictors for recurrence of drug use among males on probation for methamphetamine use in Japan: a one-year follow-up study.
Drug Alcohol Depend Rep
March 2025
Department of Drug Dependence Research, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
Background: Methamphetamine use is related to severe health, social, and criminal challenges. However, there is limited evidence regarding the factors associated with the recurrence of drug use among individuals who have used methamphetamine, particularly within populations involved in the criminal justice system. This study aimed to identify predictors of illicit drug use at a one-year follow-up among males in Japan who have used methamphetamine and are involved in the criminal justice system.
View Article and Find Full Text PDFExploring the Relationship Between VMAT2 and DAT Expression, Psychotic Experiences, Craving, and Treatment Motivation in Male Patients with Methamphetamine Use Disorder.
J Clin Med
November 2024
Department of Psychiatry, Faculty of Medicine, Sakarya University, 54290 Sakarya, Türkiye.
We aimed to examine the relationship of Dopamine transporter (DAT) and vesicular monoamine transporter (VMAT-2) gene and protein levels with psychic experiences and other clinical parameters in individuals with Methamphetamine Use Disorder (MUD). This study included 50 males diagnosed with MUD and 50 males as a smoking control (SC) and nonsmoking control (NSC). Community Assessment of Psychic Experiences (CAPE) was administered to patients and controls; Addiction Profile Index, Treatment Motivation Questionnaire, and Substance Craving Scale were administered only to the patient group.
View Article and Find Full Text PDFIdentifying methamphetamine use predictors in HIV infection: Immune-dopaminergic signatures in peripheral leukocytes and the role of COMT genotype.
Brain Behav Immun Health
December 2024
San Diego Biomedical Research Institute, San Diego, CA, 92121, USA.
Article Synopsis
- The development of translational biomarkers is essential for diagnosing and monitoring diseases, especially in complex conditions like HIV-associated neurocognitive impairment (NCI), where diverse factors can complicate analysis.
- Substance use, particularly methamphetamine (METH), exacerbates cognitive deficits in people living with HIV (PWH), and current biomarkers fail to highlight the differences in their disease trajectory compared to non-users.
- Researchers hypothesized that certain signatures in blood cells related to dopamine levels can differentiate between HIV+ METH users and other groups, revealing neuroimmune mechanisms linked to depression and aiding in the identification of affected individuals through specific gene variations.
Health disparities and injection drug use behaviors among adults with and without disabilities in the National Survey on drug use and health, 2015-2019.
Disabil Health J
January 2025
School of Social Work, Arizona State University, AZ, USA.
Background: Little is known about the prevalence of injection drug use in people with disabilities (PWD) when compared by disability type and to other adults without disabilities.
Objective Or Hypothesis: The prevalence of past-year injection drug use will be higher in adults with a reported disability than adults without any reported disability.
Methods: This study consisted of secondary analyses of data from the 2015-2019 National Survey of Drug Use and Health.
Prevalence of Methamphetamine (Mkpurummiri) use in south east Nigeria: a community-based cross-sectional study.
BMC Public Health
September 2024
Department of Industrial Mathematics and Applied Statistics, Ebonyi State University, Abakaliki, Nigeria.
Article Synopsis
- Methamphetamine (MA) use is prevalent in south east Nigeria, with a reported prevalence of 21.8% among surveyed adolescents and adults, primarily driven by depression and commonly administered through inhalation.
- The study utilized a descriptive cross-sectional survey with 371 respondents and analyzed data using various statistical methods to identify factors associated with MA use.
- Key control measures identified included self-control, parental monitoring, drug education, and legal oversight, while users were characterized by aggressive behavior and living off-campus, which correlated with lower MA use likelihood.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!