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Assessment of cardio-oncology knowledge and practice among healthcare providers in Saudi Arabia: a comprehensive nationwide survey.
Cardiooncology
December 2024
Department of Medical Oncology, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Introduction: The evolving field of oncology necessitates effective management of cancer-related cardiovascular diseases. In Saudi Arabia, the incidence of cancer is rising, and there is a critical need for cardio-oncology services to address cancer treatment-related cardiovascular toxicity. This study aimed to evaluate the knowledge and practices of healthcare providers (HCPs) in Saudi Arabia regarding cardio-oncology.
View Article and Find Full Text PDFExposure to the Polychlorinated biphenyl mixture Aroclor 1254 elicits neurological and cardiac developmental effects in early life stage zebrafish (Danio rerio).
Chemosphere
January 2025
University of North Texas, Department of Biological Sciences and Advanced Environmental Research Institute, Denton, TX, 76203, USA. Electronic address:
The goal of this study was to compare the bioaccumulation of the PCB mixture Aroclor 1254 in zebrafish to cardiac and neurologic outcomes. The establishment of effect concentrations (ECs) for cardiac and neurotoxic effects of PCBs in early life stage fish is challenging due to a lack of measured PCB concentrations in test media (e.g.
View Article and Find Full Text PDFChallenges in the implementation of cardio-oncology trials: lessons learnt from investigating statins in the prevention of anthracycline cardiotoxicity.
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Victorian Heart Institute, Monash University, Melbourne, VIC, Australia.
Despite advanced in targeted cancer therapies, anthracyclines remain essential in treating various malignancies, albeit with risks of cancer therapy-related cardiac dysfunction (CTRCD). Out of the myriad of mitigation strategies for CTRCD, statins are an attractive preventive therapy for anthracycline associated CTRCD given their widespread availability, cheap costs and added benefit of atherosclerotic cardiovascular disease (ASCVD) risk reduction. Recent trials of PREVENT, SPARE-HF, and STOP-CA investigated atorvastatin's efficacy in preventing CTRCD, with mixed outcomes.
View Article and Find Full Text PDFChanges in tumor and cardiac metabolism upon immune checkpoint.
Basic Res Cardiol
December 2024
Department of Dermatology, Venereology and Allergology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Cardiovascular disease and cancer are the leading causes of death in the Western world. The associated risk factors are increased by smoking, hypertension, diabetes, sedentary lifestyle, aging, unbalanced diet, and alcohol consumption. Therefore, the study of cellular metabolism has become of increasing importance, with current research focusing on the alterations and adjustments of the metabolism of cancer patients.
View Article and Find Full Text PDFThe role and mechanism of TXNDC5 in cardio-oncology: Killing two birds with one stone?
Curr Probl Cardiol
December 2024
Key Laboratory of Chinese Internal Medicine of Ministry of Education, Beijing University of Chinese Medicine, Beijing, China; Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China; College of Integrated Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, China. Electronic address:
Article Synopsis
- * Research in this field has expanded to explore connections between cardiovascular diseases and cancer, particularly the role of TXNDC5, a protein linked to both conditions.
- * The review analyzes how TXNDC5 influences the development of cancer and cardiovascular diseases, and discusses potential new treatment strategies targeting this protein to improve cancer therapy and cardio-oncology advancements.
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