Decision regret among women considering planned oocyte cryopreservation: a prospective cohort study.

J Assist Reprod Genet

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco School of Medicine, 499 Illinois Street, 6th Floor, San Francisco, CA, 94158, USA.

Published: June 2023

AI Article Synopsis

  • - The study aimed to evaluate the level of decision regret among women considering egg freezing, comparing those who went through with it versus those who chose not to, and to identify factors that could predict future regret.
  • - Results showed that only 9% of women who froze their eggs experienced moderate-to-severe regret, while a high 51% of those who didn't freeze felt regret over their decision.
  • - Key factors reducing regret for those who froze their eggs included having sufficient information at the initial consultation and focusing on future parenthood; lack of funds and time were primary reasons for not freezing, leading to increased regret.

Article Abstract

Purpose: To (1) prospectively characterize the incidence of decision regret among women considering planned oocyte cryopreservation (planned OC), comparing those who pursued treatment vs those who did not freeze eggs, and (2) to identify baseline predictors for future decision regret.

Methods: A total of 173 women seen in consultation for planned OC were followed prospectively. Surveys were administered at (1) baseline (< 1 week after initial consultation) and (2) follow-up, 6 months after planned OC among participants who froze eggs or 6 months following consultation in the absence of further communication to pursue treatment. The primary outcome was the incidence of moderate-to-severe decision regret, indicated by a Decision Regret Scale score > 25. We also examined predictors of regret.

Results: The incidence of moderate-to-severe regret over the decision to freeze eggs was 9% compared to 51% over the decision not to pursue treatment. Among women who froze eggs, adequacy of information at baseline to decide about treatment (aOR 0.16, 95% CI 0.03, 0.87) and emphasis on future parenthood (aOR 0.80, 95% CI 0.66, 0.99) were associated with reduced odds of regret. Forty-six percent of women who froze eggs regretted not doing so earlier. Among women who did not freeze eggs, the primary reasons were financial and time constraints, correlating with increased odds of decision regret in an exploratory analysis.

Conclusions: Among women undergoing planned OC, the incidence of decision regret is low compared to the regret confronting women seen in consultation for planned OC but who do not pursue treatment. Provider counseling is key to offset the regret risk.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310667PMC
http://dx.doi.org/10.1007/s10815-023-02789-wDOI Listing

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