Background: Chronic pain is common in cirrhosis; however, the mechanistic classifications are not well characterized. Nociplastic pain, for instance, is associated with comorbid nonpain symptoms and responds to different treatments than nociceptive pain.
Methods: We conducted a survey study in February 2022 of adult patients with cirrhosis at the University of Michigan (N = 238) to evaluate pain widespreadedness, associated nociplastic symptoms, and pain intensity.
Findings: Pain and pain widespreadedness were associated with mood and cognitive disturbance, fatigue, sleep difficulty, and physical and social functioning. Patient-reported Outcomes, such as body maps, can be useful to phenotype patients for pain mechanisms.
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| http://dx.doi.org/10.1097/HC9.0000000000000120 | DOI Listing |
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