AI Article Synopsis

  • The study investigated the effects of intermittent fasting (IF) on patients with non-alcoholic fatty liver disease (NAFLD) and prediabetes.
  • The research involved 95 patients, split into two groups: one with obesity and the other with prediabetes, both having a BMI between 30.0 kg/m² and 34.5 kg/m².
  • Results showed that IF significantly improved body measurements and metabolic markers after 6 and 12 months, with additional benefits when metformin was used following the fasting period.

Article Abstract

Objective: The aim: To study intermittent fasting (IF) treatment in patients with non-alcoholic fatty liver disease (NAFLD) and prediabetes.

Patients And Methods: Materials and methods: Patients with NAFLD (n=95) were examined. The patients were divided into 2 groups: Group 1 - NAFLD with obesity, Group 2 - NAFLD and prediabetes. All patients in both groups had Body mass index (BMI) within the 2nd degree of obesity range (30.0 kg/m2 to 34.5 kg/m2).

Results: Results: The effect of IF on anthropometric parameters, carbohydrate and lipid levels in patients with NAFLD with obesity and NAFLD with prediabetes, 6 and 12 months after treatment is shown.

Conclusion: Conclusions: Intermittent fasting has a statistically significant effect on anthropometric parameters in NAFLD with obesity and NAFLD with prediabetes. Metformin administration after intermittent fasting in 12 months showed a statistically significant improvement in lipid and carbohydrate profiles.

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Source
http://dx.doi.org/10.36740/WLek202303109DOI Listing

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