Objective: To assess the safety and efficacy of balloon dilatation under dual guidance using fluoroscopy and bronchoscopy for treating bronchial stenosis following lung transplantation (LT), and to elucidate the factors associated with patency after the procedure.
Materials And Methods: From September, 2012, to April, 2021, 50 patients (mean age ± standard deviation, 54.4 ± 12.2 years) with bronchial stenosis among 361 recipients of LT were retrospectively analyzed. The safety of balloon dilatation was assessed by evaluating procedure-related complications. Efficacy was assessed by evaluating the technical success, primary patency, and secondary patency. Primary and secondary cumulative patency rates were calculated using the Kaplan-Meier method. The factors associated with patency after the procedure were evaluated using multivariable Cox hazard proportional regression analysis.
Results: In total, 65 bronchi were treated with balloon dilatation in 50 patients. The total number of treatment sessions was 277 and the technical success rate was 99.3% (275/277 sessions). No major procedure-related complications were noted. During the mean follow-up period of 34.6 ± 30.8 months, primary patency was achieved in 12 of 65 bronchi (18.5%). However, the patency rate improved to 76.9% (50 of 65 bronchi) after repeated balloon dilatation (secondary patency). The 6-month, 1-year, 3-year, and 5-year secondary patency rates were 95.4%, 90.8%, 83.1%, and 78.5%, respectively. The presence of clinical symptoms was a significant prognostic factor associated with reduced primary patency (adjusted hazard ratio [HR], 0.465; 95% confidence interval [CI], 0.220-0.987). Early-stage treatment ≤ 6 months (adjusted HR, 3.588; 95% CI, 1.093-11.780) and prolonged balloon dilatation > 5 min (adjusted HR, 3.285; 95% CI, 1.018-10.598) were associated with significantly higher secondary patency.
Conclusion: Repeated balloon dilatation was determined to be safe and effective for treating bronchial stenosis following LT. Early-stage treatment and prolonged balloon dilatation could significantly promote long-term patency.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157327 | PMC |
| http://dx.doi.org/10.3348/kjr.2022.0999 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
COMPARISON OF STENT GEOMETRY ACHIEVED BY DIFFERENT SIDE-BRANCH BALLOONING TECHNIQUES FOR BIFURCATION PROVISIONAL STENTING: THE CRABBIS TRIAL.
JACC Cardiovasc Interv
March 2025
Department of Cardiovascular and Pulmonary Sciences, Università Cattolica del Sacro Cuore, Rome, Italy; Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. Electronic address:
Background: "Stepwise provisional stenting" is the most adopted approach for percutaneous coronary interventions (PCI) in bifurcation lesions. During these procedures, side-branch (SB) may deserve treatment, but the best ballooning technique is still undetermined.
Objectives: To compare the stent configurations obtained by two SB ballooning sequences after the main vessel (MV) stent implantation: proximal-optimization-technique (POT)+kissing-balloon-inflation+final POT (PKP) versus POT+isolated-SB-dilation+final POT (PSP).
A 64-year-old woman had undergone subtotal stomach-preserving pancreaticoduodenectomy for locally advanced pancreatic head cancer. She had an uneventful postoperative course with no recurrence. However, approximately 18 months after surgery, she presented with recurrent abdominal pain.
View Article and Find Full Text PDFTreatment of femoropopliteal arterial lesions with excimer laser atherectomy and drug-coated balloon.
Vascular
March 2025
Sichuan Mental Health Center, The Third Hospital of Mianyang, P. R. China.
ObjectivesProximal to mid-term effects of contrast excimer laser atherectomy (ELA) + drug-coated balloon (DCB) versus PTA + drug-coated balloon (DCB) in the treatment of new lesions in the femoral popliteal segment of patients with lower extremity arteriosclerosis and occlusion.MethodsThe clinical data of 105 patients with CT-confirmed femoropopliteal segment lesions (Rutherford grades 3-6) were retrospectively analyzed. According to the computerized randomization method, 58 patients (44 males, mean 72.
View Article and Find Full Text PDFBalloon Dilatation for Congenital Nasal Pyriform Aperture Stenosis: A Novel Minimally Invasive Technique.
Indian J Otolaryngol Head Neck Surg
January 2025
Motherhood Hospital, Indiranagar, Bengaluru India.
This case report describes a case of congenital nasal pyriform aperture stenosis in a 7 day old neonate, which was managed with an endoscopic balloon dilatation. Nasal stents were not used and the child is doing well after 6 months on routine follow up.
View Article and Find Full Text PDFRe-ballooning of sealing frame for intraoperative paravalvular leak during rapid deployment aortic valve replacement: a report of two cases.
Gen Thorac Cardiovasc Surg Cases
March 2025
Division of Cardiovascular Surgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, 980-8574, Japan.
Background: Rapid deployment aortic valve replacement (RDAVR) has been widely adopted, but concerns about postoperative paravalvular leak (PVL) associated with its use remain. PVL is linked to an increased risk of long-term mortality; however, there is no consensus on its treatment.
Case Presentation: Case 1: A 76-year-old female with severe aortic stenosis underwent RDAVR via median sternotomy.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!