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Post COVID-19 AA amyloidosis of the kidneys with rapidly progressive renal failure. | LitMetric

AI Article Synopsis

  • The COVID-19 pandemic has resulted in significant challenges for healthcare, with high infection rates leading to severe complications and increased mortality, mainly from lung and heart issues.
  • Many critically ill patients also experience kidney complications, such as acute kidney injury (AKI) and rare conditions like collapsing focal segmental glomerulosclerosis (FSGS).
  • The case report discusses a patient with AA amyloidosis and rapid kidney failure alongside congestive heart failure, linking these complications to moderate COVID-19, which suggests potential associations needing further research.

Article Abstract

Coronavirus disease 2019 (COVID-19) pandemic has taken the world by a storm, posing a gruelling challenge to the medical fraternity globally. Besides its very high infectivityinfectivity, significant organ dysfunction occurs in critically ill COVID-19 patients, leading to severe morbidity and mortality. Pulmonary involvement is the leading cause of death in these patients to be followed by the cardiovascular involvement. Kidney involvement due to COVID-19 is becoming more discernible with AKI adversely affecting the outcome. Besides AKI, a few cases of collapsing FSGS in genetically vulnerable patients and thrombotic microangiopathies have been reported as well. We report a case of AA amyloidosis of the kidney with a rapidly progressive renal failure and congestive heart failure with preserved left ventricular functions, which complicated a moderate COVID-19 pneumonia providing some clues to a possible association of this novel virus disease with this complication, which needs to be confirmed in future studies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114959PMC
http://dx.doi.org/10.1080/19336896.2023.2201151DOI Listing

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