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Use of fractal [corrected] analysis for evaluation of liver structure and function in rats in vivo.

Bull Exp Biol Med

February 2009

Department of Experimental Cryomedicine, Institute of Problems of Cryobiology and Cryomedicine, National Academy of Sciences of Ukraine, Kharkov, Ukraine.

Fractal [corrected] and morphometrical analysis of images obtained by life-time photo- and videorecording of microhemocirculatory changes in the rats in health, experimental cirrhosis, and variants of its treatment was carried out. Differences in the fractional dimensions of the studied organs were significant and correlated with morphological values. This suggests fractal [corrected] analysis for the diagnosis and prediction of hepatic tissue status in vivo.

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Electron-microscopic and radioautographic investigation showed the ability of brain capillary endotheliocytes for retaining functional activity in total ishemia. Administration of serotonin adipinate in an early postoperative period supports intracellular processes and plays a protective role.

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Microhemocirculatory changes in the ischemic myocardium concurrently exposed to low-intensive He-Ne laser, finoptin (145 micrograms/kg body weight) and perlinganit (25 micrograms/kg body weight) were experimentally studied in 50 Chinchilla rabbits. Drug and laser were daily used after 30-day inactivity for 7 days. There were anti-ischemic effects of He-Ne laser and perlinganit in increasing the number of functioning capillaries and in enhancing their functional activity.

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