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AI-assisted digital video analysis reveals changes in gait among three-day event horses during competition.
J Equine Vet Sci
January 2025
University of Florida Department of Animal Sciences, 2250 Shealy Dr., Gainesville, FL, 32611 United States; UF Genetics Institute, 2033 Mowry Rd., Gainesville, FL, 32611 United States. Electronic address:
The value and welfare of performance horses is closely tied to locomotor behaviors, but we lack objective and quantitative measures for these characteristics, and qualitative approaches for assessing gait do not provide measures suitable for large-scale biomechanical research studies. Digital video analysis utilizing artificial intelligence-based strategies holds promise to meet the need for an economical, accurate, repeatable and objective technique for field quantification of equine locomotion. Here we describe pilot work using a consumer-level digital video camera to capture high-resolution and high-speed videos of horses moving at the trot during mandatory inspections for international-level eventing competitions.
View Article and Find Full Text PDFInflammation and response to bacterial infection as potential drivers of equine odontoclastic tooth resorption and hypercementosis: A proteomics insight.
Equine Vet J
January 2025
University of Liverpool, Institute of Life Course and Medical Sciences, William Henry Duncan Building, Liverpool, UK.
Background: Equine dental diseases significantly impact a horse's overall health, performance and quality of life. They can result in secondary infections and digestive disturbances, potentially leading to colic. A recently described disease affecting the incisors of horses is equine odontoclastic tooth resorption and hypercementosis (EOTRH).
View Article and Find Full Text PDFObjective: Pergolide, labeled for the treatment of pituitary pars intermedia dysfunction, is 90% protein bound and might cause a decrease in blood thyroid hormone concentrations by displacing them from binding proteins. This study investigated the effect of pergolide on the equine thyroid function.
Methods: This was an analytic, observational, cohort study.
Open-label, controlled, phase 2 clinical trial assessing the safety, efficacy, and pharmacokinetics of INM004 in pediatric patients with Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome.
Pediatr Nephrol
November 2024
Inmunova SA, Ciudad Autónoma de Buenos Aires, Argentina.
Background: Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome (STEC-HUS) is a severe condition mainly affecting children. It is one of the leading causes of acute kidney injury in the pediatric population. There is no established therapy for this disease.
View Article and Find Full Text PDFInvestigating the impact of extracellular vesicle addition during IVM on the fertilization rate of equine oocytes following ICSI.
Reprod Biol
December 2024
Department of Animal Reproduction, Anatomy and Genomics, Faculty of Animal Science, University of Agriculture in Krakow, Mickiewicza 24/28, 30-059 Krakow, Poland.
The efficacy of in vitro embryo production (IVEP) in equines is relatively limited compared to other species due to the lack of a reliable superovulation technique, limited availability of cumulus oocyte complexes (COCs), low in vitro oocyte maturation (IVM) and fertilization rates. Extracellular vesicles (EVs), which are nanoparticles involved in intercellular signaling in the ovarian environment, have shown potential as supplements to improve oocyte development during IVM. This study tested the hypothesis that EVs from small (< 20 mm) ovarian follicles could enhance fertilization rates in mares.
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