Objective: To characterise and explore the development in the number and content of urine samples sent from general practice in the North Denmark Region to the Department of Clinical Microbiology (DCM) at Aalborg University Hospital during a five-year period.
Design: A register-based study.
Setting: General practice.
Subjects: Urine samples received at DCM, Aalborg University Hospital from general practice between 2017 and 2022.
Main Outcome Measures: Number and content of urine samples.
Results: A total of 255,271 urine samples from general practice were received at DCM, with 76.1% being from female patients. Uropathogens were identified in 43.0% of the samples. During the five-year period, a 23.0% increase in the number of urine samples per person (incidence rate ratio (IRR) 1.23, 95% CI 1.21-1.25) was observed. A slight increase in the proportion of positive cultures (risk ratio (RR) 1.03, 95% CI 1.01-1.05) was seen. No notable change in the patient population (age, gender) was observed. Overall, was the most identified uropathogen (60.4%) followed by spp. (8.7%) and spp. (7.7%). Distribution of the various uropathogens differed slightly depending on patient gender and age, importantly was less frequently observed in males aged >65 years.
Conclusion: During the past five years an increasing amount of urine cultures have been requested at DCM from general practice. Importantly, the cause(s) of this increasing demand needs to be explored further in future studies.
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http://dx.doi.org/10.1080/02813432.2023.2196546 | DOI Listing |
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Department of Geriatrics, Zhongshan Hospital Xiamen University, Fujian, People's Republic of China.
Introduction: What interventions effectively prevent postoperative stenosis following endoscopic resection (ER) of superficial esophageal cancer? This study aimed to identify effective interventions or combinations through a systematic review and network meta-analysis.
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JAMA Netw Open
January 2025
Division of Surgical Oncology, University of Utah, Salt Lake City.
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January 2025
Medical Histology and Cell Biology Department, Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt.
Gestational diabetes mellitus (GDM) significantly disrupts placental structure and function, leading to complications such as intrauterine growth restriction (IUGR) and preeclampsia. This study aimed to investigate the effects of GDM on placental histology, angiogenesis, and oxidative stress, as well as evaluate metformin's protective role in mitigating these changes. A total of 60 pregnant Sprague-Dawley rats were divided into four groups: control, metformin-treated, GDM, and GDM with metformin.
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Department of Public and Occupational Health, Amsterdam UMC Location VUMC, Amsterdam, the Netherlands.
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J Orthop Surg (Hong Kong)
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Sports Medicine Center, West China Hospital, Sichuan University, Chengdu, China.
Objective: Revision surgeries for periprosthetic joint infections (PJIs) in arthroplasty can follow either one- or two-stage treatment protocols. Previous studies have reported similar reinfection rates and reductions in complication rates for both treatment options. However, the literature on the selection of one protocol is still controversial.
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