Aims: Cardiac amyloidosis (CA) is an under-diagnosed cause of heart failure (HF) and has a worse prognosis than other forms of HF. The frequency of death or rehospitalization following discharge for acute heart failure (AHF) in CA (relative to other causes) has not been documented. The study aims to compare hospital readmission and death rates 90 days after discharge for AHF in patients with vs. without CA and to identify risk factors associated with these events in each group.
Methods And Results: Patients with HF and CA (HF + CA+) were recruited from the ICREX cohort, after screening of their medical records. The cases were matched 1:5 by sex and age with control HF patients without CA (HF + CA-). There were 27 HF + CA + and 135 HF + CA- patients from the ICREX cohort included in the study. Relative to the HF + CA- group, HF + CA+ patients had a higher heart rate (P = 0.002) and N-terminal prohormone of brain natriuretic peptide levels (P < 0.001) and lower blood pressure (P < 0.001), weight, and body mass index values (P < 0.001) on discharge. Ninety days after discharge, the HF + CA+ group displayed a higher death rate, a higher all-cause hospital readmission rate, and a higher hospital readmission rate for AHF. Death and hospital readmissions occurred sooner after discharge in the HF + CA+ group than in the HF + CA- group.
Conclusions: The presence of CA in patients with HF was associated with a three-fold greater risk of death and a two-fold greater risk of all-cause hospital readmission 90 days after discharge. These findings emphasize the importance of close, active management of patients with CA and AHF.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192232 | PMC |
http://dx.doi.org/10.1002/ehf2.14337 | DOI Listing |
Pacing Clin Electrophysiol
December 2024
Servei de Cardiologia, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, España.
Introduction: Right ventricular (RV) pacing can impair left ventricular function and cause heart failure, known as pacing-induced cardiomyopathy (PICM). Upgrade to cardiac resynchronization (CRT) is its usual treatment; recently left bundle branch area pacing (LBBAP) has emerged as a potential alternative. Deep septal pacing (DSP), a simplified alternative to LBBAP, is still able to achieve narrower paced QRS than during conventional RV pacing.
View Article and Find Full Text PDFPacing Clin Electrophysiol
December 2024
Department of Cardiology, Cardinal Wyszynski Hospital in Lublin, Lublin, Poland.
Background: Cardiac implantable devices (CIED) such as pacemakers, implantable cardioverter-defibrillators, or cardiac resynchronization devices are implanted in selected patients with bradyarrhythmia and advanced heart failure. The invasive character of these procedures poses a risk of early complications such as pneumothorax, bleeding, infections, or dislocations.
Aims: There are no available data that analyzed the impact of the organization of procedures on the early complications risk after permanent pacing procedures.
Circ Heart Fail
December 2024
Department of Cardiology, Aarhus University Hospital, Denmark. (K.B.-H., N.G., K.H.C., R.N., K.L., H.W.).
J Exp Biol
December 2024
Alfred Wegener Institute Helmholtz Center for Polar and Marine Research, Sections Integrative Ecophysiology and Deep-Sea Ecology & Technology, Am Handelshafen 12, 27515 Bremerhaven, Germany.
Increasing frequencies of heatwaves threaten marine ectotherm species but not all alike. In exposed habitats, some species rely on a higher capacity for passive tolerance at higher temperatures, thereby extending time-dependent survival limits. Here we assess how the involvement of the cardiovascular system in extended tolerance at the margins of the thermal performance curve is dependent on warming rate.
View Article and Find Full Text PDFAm Heart J Plus
December 2024
National Institute of Cardiology Ignacio Chavez, Coronary Care Unit, Mexico City, Mexico.
Background And Aims: Heart failure with preserved ejection fraction (HFpEF) is an increasingly common clinical syndrome, estimated to constitute approximately 50 % of all heart failure (HF) cases. Nonetheless, registries from specific geographic areas, as Latin America, are lacking. The present study aims to report the underlying causes, comorbidities, treatment patterns and outcomes of patients with HFpEF in a large cardiovascular center in Mexico City.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!