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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084573PMC
http://dx.doi.org/10.1177/20406223231164523DOI Listing

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Background: The World Health Organization recommends continuation with the failing second-line regimen if third-line option is not available. We investigated treatment outcomes among people living with HIV in Asia who continued with failing second-line regimens compared with those who had treatment modifications after failure.

Methods: Treatment modification was defined as a change of two antiretrovirals, a drug class change or treatment interruption (TI), all for >14 days.

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