The purpose of this study was to determine the chemical composition of the essential oil of from Morocco using the GC-MS technique and assess the antibacterial effects against seven pathogenic bacteria strains isolated from the food origins of , , three serotypes of (O114H8K11, O127K88ac, O127H40K11) and Tests of sensitivity were carried out on a solid surface using the Disc Diffusion Method. Results showed that and were sensitive to essential oil. Minimum inhibitory concentrations (MIC) were determined using the method of agar dilution. The antibacterial results showed that four strains (three serotypes of , and ) were remarkedly sensitive to essential oil, giving MIC values of 88.7 µg/mL and 177.5 µg/mL. The molecular docking of the main oil products with the target protein 1VLY, showed that eucalyptol and linalyl acetate bind efficiently with the active site of the target protein. In particular, eucalyptol showed a higher activity than gentamicin used as positive control with a binding energy of -5.72 kcal/mol and -5.55 kcal/mol, respectively.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097330 | PMC |
| http://dx.doi.org/10.3390/plants12071571 | DOI Listing |
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