Current Management of Stage IIIA (N2) Non-Small-Cell Lung Cancer: Role of Perioperative Immunotherapy, and Tyrosine Kinase Inhibitors.

Thorac Surg Clin

Section of Thoracic Surgery, Department of Surgery, University of Chicago Medicine, Room S-546/MC 5047, 5841 South Maryland Avenue, Chicago, IL 60637, USA. Electronic address:

Published: May 2023

There have been numerous recent advances in the treatmetn of stage IIIA non-small cell lung cancer. The most significant involve the addition of targeted therapies adn immune checkpoint inhibitors into perioperative care. These exciting advances are improving survival in this challenging patient population, but some-decade old controveries around the definition of resectability, prognositic importance of tumor response to induction therapy, and the role of pneumonectomy persist.

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http://dx.doi.org/10.1016/j.thorsurg.2023.01.006DOI Listing

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