Polymer nanomaterials for use as adjuvant surgical tools.

Wiley Interdiscip Rev Nanomed Nanobiotechnol

Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, Maryland, USA.

Published: July 2023

AI Article Synopsis

  • Materials used in surgical and clinical practice often struggle with issues like poor mechanical stability and difficulty adhering to complex tissue surfaces, which limits their effectiveness.
  • To address these challenges, research is focusing on polymer-derived nanomaterials that can enhance surgical outcomes through various applications like wound dressings, tissue adhesives, and sealants.
  • This review highlights both the practical applications of these nanomaterials and the innovative design strategies used in their fabrication to improve surgical treatments.

Article Abstract

Materials employed in the treatment of conditions encountered in surgical and clinical practice frequently face barriers in translation to application. Shortcomings can be generalized through their reduced mechanical stability, difficulty in handling, and inability to conform or adhere to complex tissue surfaces. To overcome an amalgam of challenges, research has sought the utilization of polymer-derived nanomaterials deposited in various fashions and formulations to improve the application and outcomes of surgical and clinical interventions. Clinically prevalent applications include topical wound dressings, tissue adhesives, surgical sealants, hemostats, and adhesion barriers, all of which have displayed the potential to act as superior alternatives to current materials used in surgical procedures. In this review, emphasis will be placed not only on applications, but also on various design strategies employed in fabrication. This review is designed to provide a broad and thought-provoking understanding of nanomaterials as adjuvant tools for the assisted treatment of pathologies prevalent in surgery. This article is categorized under: Implantable Materials and Surgical Technologies > Nanomaterials and Implants Implantable Materials and Surgical Technologies > Nanoscale Tools and Techniques in Surgery.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10524211PMC
http://dx.doi.org/10.1002/wnan.1889DOI Listing

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