AI Article Synopsis
- The case study discusses a rare adrenal neoplasm misidentified as pheochromocytoma but found to be an adrenal cortical tumor upon histological examination.
- The diagnosis was supported by electron microscopy, which showed neuroendocrine granules alongside lipid droplets in the tumor cells.
- Following laparoscopic surgery to remove the tumor, the patient's urine levels of metanephrine and normetanephrine returned to normal, highlighting the importance of accurate diagnosis when symptoms and lab results differ from histological findings.
Article Abstract
Clinical and biochemical presentation of adrenal tumors may rarely conflict with their histologic features. In the present report, we describe a rare case of adrenal neoplasm clinically and biochemically labeled as pheochromocytoma which at histologic examination resulted adrenal cortical tumor. The neoplasm was examined with the electron microscope which revealed the presence of electron-dense neuroendocrine-type granules next to intracytoplasmic lipid droplets. The patient underwent laparoscopic left adrenalectomy which leads to normalization of 24 h urinary metanephrine and normetanephrine. This exceptional entity should be taken into consideration when the clinical and laboratory features conflict with the histological examination. The pathologist can clarify the mixed nature of the tumor by means of the identification of neuroendocrine granules at the electron microscope examination.
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| http://dx.doi.org/10.1080/01913123.2023.2201314 | DOI Listing |
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