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A copper-catalyzed [3+2] annulation of -acyl ketoximes with 2-aryl malonates for the concise synthesis of 3-aryl-4-pyrrolin-2-ones has been developed. The advantage of this method lies in the use of -acyl oximes as an internal oxidant to generate the nucleophilic enamines and electrophilic -quinone methides concurrently. The subsequent nucleophilic addition undergoes selectively on the α-C of malonates.
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