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Anomalous glucose-responsive rheological changes in a boronic acid-modified hyaluronan. | LitMetric

Anomalous glucose-responsive rheological changes in a boronic acid-modified hyaluronan.

Chem Commun (Camb)

Faculty of Pharmacy and Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan.

Published: April 2023

Herein, we report anomalous glucose (Glc)-responsive gelation/solation in 3-aminophenylboronic acid-modified hyaluronic acid. With 5-20 mM Glc, gelation occurred, resulting in the formation of crosslinks Glc, which could reversibly bind to the two boronic acid sites. Solation was induced at Glc concentrations of >80 mM.

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Source
http://dx.doi.org/10.1039/d3cc01020aDOI Listing

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