AI Article Synopsis
- The study explored how smoking affects overall mortality rates in individuals with Parkinson's disease using data from the Korean National Health Insurance Service.
- Analysis of 26,080 PD patients showed no significant link between smoking status and death rates, with smokers having somewhat higher risks for certain cancers but lower death rates from neurological causes.
- The findings indicate that while smoking doesn't appear to increase overall mortality in PD patients, it's still not advisable for those with the disease due to increased cancer risks.
Article Abstract
We aimed to investigate the association between smoking status and all-cause mortality of Parkinson's disease (PD). Among the whole nationwide population data from Korea National Health Insurance Service, newly diagnosed PD was selected, and all-cause mortality was evaluated. The systematic review was performed through a literature search on the PubMed, EMBASE, and Cochrane Central Register of Controlled Trials databases. Among 26,080 individuals with PD, there was no significant association between smoking status and all-cause mortality in a nationwide cohort study (ex-smoker, HR 0.1.03, 95% CI 0.97-1.10; current smoker, HR 1.06, 95% CI 0.96-1.16). The systematic review, including six prospective cohort studies, also found a nonsignificant association. PD smokers tended to have fewer deaths from neurologic causes but were significantly more likely to die from smoking-related cancers such as lung cancer. We presented a nonsignificant association between smoking and mortality of PD, and cigarette smoking is not recommended in individuals with PD.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085986 | PMC |
| http://dx.doi.org/10.1038/s41531-023-00486-0 | DOI Listing |
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