Epigenetic dysregulation including DNA methylation and histone modifications is being increasingly recognized as a promising biomarker for the diagnosis and prognosis of cancer. Herein, we devised a label-free analytical toolbox comprising IR, UV-vis, CD spectroscopy, and cyclic voltammetry, which is capable to differentiate significantly hyper-methylated breast cancer chromosomes from the normal breast epithelial counterparts.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.jpcb.3c00147 | DOI Listing |
Publication Analysis
Top Keywords
breast cancer
8
cancer chromosomes
8
label-free physical-analytical
4
physical-analytical techniques
4
techniques reveal
4
reveal epigenetic
4
epigenetic modifications
4
modifications breast
4
chromosomes epigenetic
4
epigenetic dysregulation
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!