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| http://dx.doi.org/10.4103/JCAS.JCAS_84_21 | DOI Listing |
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MOHS Patients Can Reliably Estimate Preoperative Non-Melanoma Skin Cancer Size.
Skinmed
January 2025
Department of Dermatology, University of Cincinnati, Cincinnati, OH.
As the presurgical size and anatomic location of non-melanoma skin cancer correlates to the complexity of Mohs micrographic surgery (MMS), patients are frequently asked to self-report their preoperative tumor size to aid in efficient scheduling and triage. We aimed to assess the accuracy of patient's self-reported lesion measurements prior to MMS by comparing patient's estimates of lesion size to the measurements taken by a Mohs surgeon. We conducted a retrospective chart review of 1,000 patients who underwent MMS and self-reported their lesion size at a preoperative telehealth visit.
View Article and Find Full Text PDFPediatric and adolescent cancer disparities in the Middle East and North Africa (MENA) region: incidence, mortality, and survival across socioeconomic strata.
BMC Public Health
December 2024
Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Background: Cancer is one of the leading causes of death in children and adolescents, with a significant concentration in low and middle-income countries. Previous research has identified disparities in cancer incidence and mortality based on a country's level of development. The Middle East and North Africa (MENA) region comprises of countries with heterogeneous income and development levels.
View Article and Find Full Text PDFComparison of HDR-brachytherapy and tomotherapy for the treatment of non-melanoma skin cancers of the head and neck.
Radiother Oncol
December 2024
Medical Physics Unit, IRCCS, Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Italy. Electronic address:
Purpose: This study aims to investigate and compare High Dose Rate Brachytherapy (HDR-BT) with Helical Tomotherapy (HT) treatment plans. The focus is on small target volumes near radiation-sensitive organs in the ocular region, to evaluate the advantages of these techniques in treating skin cancer.
Methods: This retrospective observational analysis included patients who underwent skin cancer HDR-BT Freiburg flap treatment between 2019 and 2023.
Generation and characterization of CRISPR-Cas9-mediated XPC gene knockout in human skin cells.
Sci Rep
December 2024
Univ. Grenoble Alpes, CEA, Inserm, IRIG, UA13 BGE, Biomics, Grenoble, 38000, France.
Xeroderma pigmentosum group C (XPC) is a versatile protein crucial for sensing DNA damage in the global genome nucleotide excision repair (GG-NER) pathway. This pathway is vital for mammalian cells, acting as their essential approach for repairing DNA lesions stemming from interactions with environmental factors, such as exposure to ultraviolet (UV) radiation from the sun. Loss-of-function mutations in the XPC gene confer a photosensitive phenotype in XP-C patients, resulting in the accumulation of unrepaired UV-induced DNA damage.
View Article and Find Full Text PDFSuprathel Versus Hypafix in the Management of Split-Thickness Donor Site Wounds in the Elderly: A Randomised Controlled Trial.
Eur Burn J
October 2024
St. Andrew's Centre for Plastic Surgery and Burns, Mid and South Essex NHS Foundation Trust, Chelmsford CM1 7E, UK.
(1) Background: Effective wound management aims for expedited healing, improved functional and scar outcomes, and reduced complications including infection. Delayed wound healing remains a prevalent problem in the elderly. Suprathel is a synthetic absorbable skin substitute and an attractive option in partial thickness wounds.
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