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Post acne erythema (PAE) is a common sequela of acne inflammation, and it refers to telangiectasia and erythematous lesions remaining after the acne treatment. Although some PAE may improve over time, persisting PAE might be esthetically undesirable for patients. The efficacy of various treatment options for PAE has been investigated in many studies but there exists no gold standard treatment modality.
View Article and Find Full Text PDFCell salvage for the management of postpartum haemorrhage.
Cochrane Database Syst Rev
December 2024
Liverpool Reviews and Implementation Group, Department of Health Data Science, University of Liverpool, Liverpool, UK.
Rationale: Postpartum haemorrhage (PPH), defined as a blood loss of 500 mL or more within 24 hours of birth, is the leading global cause of maternal morbidity and mortality. Allogenic blood transfusions are a critical component of PPH management, yet are often unfeasible, particularly in resource-poor settings where maternal morbidity is highest. Autologous cell salvage in the management of PPH has been proposed to combat limitations in access to allogenic blood and potential transfusion-related risks.
View Article and Find Full Text PDFBioactive electrospun polylactic acid/chlorogenic acid-modified chitosan bilayer sponge for acute infection wound healing and rapid coagulation.
Biomater Sci
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Medical Research center, the Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen 518033, China.
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View Article and Find Full Text PDFAssociation between IV and topical tranexamic acid use and periprosthetic joint infections in hip and knee arthroplasty: a retrospective study.
BMC Musculoskelet Disord
December 2024
Department of Orthopaedic Surgery, Kaohsiung Chang Gung Memorial Hospital, No. 123, Dapi Road, Niaosong District, Kaohsiung, 833, Taiwan.
Article Synopsis
- Anemia and blood transfusions increase the risk of periprosthetic joint infections (PJI), and tranexamic acid (TXA) is known to reduce surgery-related blood loss and transfusions.
- A retrospective study involving over 8,000 patients examined the effects of TXA on PJI rates following total joint arthroplasty (TJA), comparing those who received TXA (either intravenous or topical) to those who did not.
- Results indicated that TXA significantly reduced PJI occurrences (1.1% vs. 2.1%), decreased blood transfusion rates, and led to shorter hospital stays, with no significant differences in venous thromboembolism or readmission rates.
Tranexamic acid administration in total shoulder arthroplasty: a systematic review and meta-analysis.
BMC Musculoskelet Disord
December 2024
Department of Orthopaedics, West China Hospital Sichuan University, Chengdu, 610041, China.
Background: The effects of tranexamic acid (TXA) in total shoulder arthroplasty (TSA) are controversial. The objective of this study was to investigate the efficacy and safety of TXA in TSA.
Methods: A systematic review and meta-analysis of TXA in TSA was carried out, and 5 trials including 372 patients were identified from PubMed (1966 to March 2024), Cochrane Central Register of Controlled Trials (March 2024), Embase (1974 to March 2024) and Web of Science (1995 to March 2024).
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