Influences of genetically predicted and attained education on geographic mobility and their association with mortality.

Soc Sci Med

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Aging Research Center, Karolinska Institutet & Stockholm University, Stockholm, Sweden.

Published: May 2023

AI Article Synopsis

  • The study explores the link between education (both attained and genetic propensity) and geographic mobility, and how these factors impact health outcomes, particularly mortality.
  • Using data from the Swedish Twin Registry, the researchers applied statistical models to analyze the relationships among education, mobility, and mortality rates.
  • The findings indicate that higher education levels lead to greater geographic mobility, which is associated with lower mortality; however, this mortality benefit is largely due to the effects of attained education.

Article Abstract

Introduction: Both educational attainment and genetic propensity to education (PGS) have been associated with geographic mobility. Socioeconomic conditions are, in turn, associated with individuals' health. Geographic mobility could therefore lead to better health for some since it could provide better opportunities, like education. Our aim was to study how attained education and genetic predisposition for higher education are related to geographic mobility, and how they affect the association between geographic mobility and mortality.

Methods: We used data from the Swedish Twin Registry (twins born 1926-1955; n = 14,211) in logistic regression models to test if attained education and PGS predicted geographic mobility. Cox regression models were then performed to test if geographic mobility, attained education, and PGS were associated with mortality.

Results: The results show that both attained education and PGS predicted geographic mobility, in both independent and joint effect models, with higher education associated with higher mobility. Geographic mobility was associated with lower mortality in the independent effect model, but joint effect models showed that this association was completely explained by attained education.

Conclusions: To conclude, both attained education and PGS were associated with geographic mobility. Moreover, attained education explained the relationship between geographic mobility and mortality.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526346PMC
http://dx.doi.org/10.1016/j.socscimed.2023.115882DOI Listing

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