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Important efforts have been made to describe the neural and cognitive features of healthy and clinical populations. However, the neural and cognitive features of socially vulnerable individuals remain largely unexplored, despite their proneness to developing neurocognitive disorders. Socially vulnerable individuals can be characterised as socially deprived, having a low socioeconomic status, suffering from chronic social stress, and exhibiting poor social adaptation.

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Spontaneous blink-related beta power increase and theta phase reset in subthalamic nucleus of Parkinson patients during walking.

Clin Neurophysiol

May 2024

Department of Psychology (III), Julius-Maximilian-University of Würzburg, Würzburg, Germany; Department of Neurology, University Hospital of Würzburg and Julius Maximilian University of Würzburg, Würzburg, Germany. Electronic address:

Article Synopsis
  • Blink rate increases during walking in Parkinson's disease patients and is linked to dopamine levels in specific brain regions.
  • In a study, researchers monitored subthalamic nucleus (STN) activity in patients, revealing a connection between blinking, movement states, and dopamine density.
  • Results highlight that striatal dopamine influences spontaneous blinking, with significant changes in brain activity occurring specifically when patients are walking.
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Article Synopsis
  • Conducted a retrospective study of EEG measures in amyloid-positive Alzheimer's patients with MCI or dementia, analyzing data from 148 participants with multiple EEG recordings.
  • Found significant changes in EEG patterns over time, particularly increases in theta power and decreases in beta power, with more pronounced effects in the temporal and parieto-occipital brain regions; rates of change differed by disease severity.
  • Determined that two-year clinical trials should aim for a minimum sample size that can effectively measure treatment impacts on EEG outcomes, especially given the notable deterioration in MCI patients compared to those with AD dementia.
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Aberrant oscillatory activity in neurofibromatosis type 1: an EEG study of resting state and working memory.

J Neurodev Disord

August 2023

Division of Psychology, Communication and Human Neuroscience, School of Health Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

Background: Neurofibromatosis type 1 (NF1) is a genetic neurodevelopmental disorder commonly associated with impaired cognitive function. Despite the well-explored functional roles of neural oscillations in neurotypical populations, only a limited number of studies have investigated oscillatory activity in the NF1 population.

Methods: We compared oscillatory spectral power and theta phase coherence in a paediatric sample with NF1 (N = 16; mean age: 13.

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