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http://dx.doi.org/10.4103/IJO.IJO_2872_22 | DOI Listing |
Indian J Ophthalmol
April 2023
Director, Sathyan Eye Care and Coimbatore Glaucoma Foundation, Coimbatore, Tamil Nadu, India.
Ann R Coll Surg Engl
April 2018
Northern Oesophago-Gastric Cancer Unit, Royal Victoria Infirmary , Newcastle-upon-Tyne , UK.
The use of endoluminal stents to treat anastomotic leaks post oesophagogastric resection remains controversial. While some advocate stents to expedite recovery, others advise caution due to the risk of major morbidity and mortality. We describe a case of anastomotic leak following total gastrectomy for adenocarcinoma treated with a self-expanding metallic stent.
View Article and Find Full Text PDFGenome Biol Evol
February 2016
Department of Organismic Interactions, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany
Smut fungi are plant pathogens mostly parasitizing wild species of grasses as well as domesticated cereal crops. Genome analysis of several smut fungi including Ustilago maydis revealed a singular clustered organization of genes encoding secreted effectors. In U.
View Article and Find Full Text PDFDrug Metab Dispos
July 2007
Receptor Biology Laboratory, Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505, USA.
CYP1A1 and 1A2 play critical roles in the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons (PAHs) and heterocyclic aromatic amines/amides (HAAs), respectively, to electrophilic reactive intermediates, leading to toxicity and cancer. CYP1As are highly inducible by PAHs and halogenated aromatic hydrocarbons via aryl hydrocarbon receptor-mediated gene transcription. The impact of CYP1A induction on the carcinogenic and toxic potentials of environmental, occupational, dietary, and therapeutic chemicals has been a central focus of human risk evaluation and has broadly influenced the fields of cancer research, toxicology, pharmacology, and risk assessment over the past half-century.
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