Background & Objectives: Every year more than one billion people are infected and about one million people die from vector-borne diseases; of which mosquito-borne diseases remain as the world's most severe insect-borne diseases with excessive rates of morbidity and mortality. This study aimed to examine the mosquito vectors and the possible diseases transmitted by them in the Mananthavady Taluk of Wayanad, Kerala.
Methods: The area selected for the present study was Mananthavady Taluk of Wayanad district, Kerala, during 2019-2021. The collected specimen were subjected for morphological identification using taxonomic keys and were confirmed by DNA barcoding. Molecular phylogeny assessment was done for the collected species of vector mosquitoes.
Results: A total of 17 mosquito species belonging to 5 genera, Anopheles, Aedes, Culex, Mansonia and Armigereswere identified. The mitochondrial COI gene sequences generated for molecular identification of these species were submitted to NCBI GenBank.
Interpretation & Conclusion: Overall, this study extends our understanding of the molecular evolution of mosquito vectors of medical and veterinary concern, which could aid in developing biotechnological approaches used in Culicidae control programs.
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http://dx.doi.org/10.4103/0972-9062.361166 | DOI Listing |
Parasit Vectors
January 2025
University Hospital Heidelberg, Medical Faculty, Centre for Infectious Diseases, Heidelberg University, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany.
Background: Malaria remains a key contributor to mortality and morbidity across Africa, with the highest burden in children under 5. Insecticide-based vector control tools, which target the adult Anopheles mosquitoes, are the most efficacious tool in disease prevention. Due to the widespread use of these interventions, insecticide resistance to the most used classes of insecticides is now pervasive across Africa.
View Article and Find Full Text PDFMalar J
January 2025
Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Background: Foreign migrant workers from malaria-endemic regions play a critical factor in the transmission of malaria to non-endemic areas, mainly due to their mobility while seeking employment opportunities. This risk is particularly heightened in areas where malaria vectors are present.
Methods: This study aimed to investigate the malaria vectors in two sub-districts in Khon Kaen Province, known for their factory areas and the significant presence of Myanmar migrant worker communities.
Sci Rep
January 2025
Environmental Health and Ecological Sciences Department, Ifakara Health Institute, P.O. Box 74, Bagamoyo, Tanzania.
There are three Anopheles mosquito species in East Africa that are responsible for the majority of malaria transmission, posing a significant public health concern. Understanding the vector competence of different mosquito species is crucial for targeted and cost-effective malaria control strategies. This study investigated the vector competence of laboratory reared strains of East African An.
View Article and Find Full Text PDFNat Prod Bioprospect
January 2025
Chemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, Via Madonna delle Carceri, 62032, Camerino, Italy.
Mosquitoes (Diptera: Culicidae) are vectors of various pathogens of public health concern and replacing conventional insecticides remains a challenge. In this regard, natural products represent valuable sources of potential insecticidal compounds, thus increasingly attracting research interest. Commiphora myrrha (T.
View Article and Find Full Text PDFSIAM J Appl Math
January 2024
Division of Epidemiology and Biostatistics, School of Public Health, University of California Berkeley, Berkeley, CA 94704 USA.
We review existing approaches to optimizing the deployment of genetic biocontrol technologies-tools used to prevent vector-borne diseases such as malaria and dengue-and formulate a mathematical program that enables the incorporation of crucial ecological and logistical details. The model is comprised of equality constraints grounded in discretized dynamic population equations, inequality constraints representative of operational limitations including resource restrictions, and an objective function that jointly minimizes the count of competent mosquito vectors and the number of transgenic organisms released to mitigate them over a specified time period. We explore how nonlinear programming (NLP) and mixed integer nonlinear programming (MINLP) can advance the state of the art in designing the operational implementation of three distinct transgenic public health interventions, two of which are presently in active use around the world.
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