not applicable.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1159/000529010 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Predictive modeling to evaluate long-term treatment effectiveness of darvadstrocel in patients with complex perianal fistulas in Crohn's disease.
BMC Gastroenterol
December 2024
Formerly Gastroenterology Department, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Hospital Clínic de Barcelona, Barcelona, Spain.
Background: Current therapies for complex Crohn's perianal fistulas (CPF) have a limited ability to achieve long-term healing. Darvadstrocel (DVS) is an expanded allogeneic adipose-derived mesenchymal stem cell therapy that has demonstrated efficacy in treating complex CPF in clinical trials. There are, however, limited long-term comparative data with standard of care (SoC).
View Article and Find Full Text PDFHomogeneity tests of covariance for high-dimensional functional data with applications to event segmentation.
Biometrics
December 2023
Department of Mathematics, Statistics, and Computer Science, University of Illinois at Chicago, Chicago, Illinois, USA.
We consider inference problems for high-dimensional (HD) functional data with a dense number of T repeated measurements taken for a large number of p variables from a small number of n experimental units. The spatial and temporal dependence, high dimensionality, and dense number of repeated measurements pose theoretical and computational challenges. This paper has two aims; our first aim is to solve the theoretical and computational challenges in testing equivalence among covariance matrices from HD functional data.
View Article and Find Full Text PDFHost-microbiota interactions: from holobiont theory to analysis.
Microbiome
January 2019
Muséum National d'Histoire Naturelle, Institut de Systématique, Évolution, Biodiversité, ISYEB-UMR 7205-CNRS, MNHN, UPMC, EPHE, Sorbonne Universités, 57 Rue Cuvier-CP39, F-75005, Paris, France.
In the recent years, the holobiont concept has emerged as a theoretical and experimental framework to study the interactions between hosts and their associated microbial communities in all types of ecosystems. The spread of this concept in many branches of biology results from the fairly recent realization of the ubiquitous nature of host-associated microbes and their central role in host biology, ecology, and evolution. Through this special series "Host-microbiota interactions: from holobiont theory to analysis," we wanted to promote this field of research which has considerable implications for human health, food production, and ecosystem protection.
View Article and Find Full Text PDFHealth care professionals' attitudes towards population-based genetic testing and risk-stratification for ovarian cancer: a cross-sectional survey.
BMC Womens Health
December 2017
Department of Women's Cancer, EGA UCL Institute for Women's Health, University College London, 74 Huntley Street, London, WC1E 6AU, UK.
Background: Ovarian cancer is usually diagnosed at a late stage when outcomes are poor. Personalised ovarian cancer risk prediction, based on genetic and epidemiological information and risk stratified management in adult women could improve outcomes. Examining health care professionals' (HCP) attitudes to ovarian cancer risk stratified management, willingness to support women, self-efficacy (belief in one's own ability to successfully complete a task), and knowledge about ovarian cancer will help identify training needs in anticipation of personalised ovarian cancer risk prediction being introduced.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!