AI Article Synopsis
- Gymnema sylvestre is a medicinal plant in India known for its use in treating diabetes, but it currently lacks organized cultivation and is mostly harvested from the wild.
- A study analyzed the genetic diversity of 118 accessions from 11 wild populations using DNA markers, revealing significant genetic variation at the species level but low variation among populations.
- The findings suggested two main genetic clusters based on geographic regions, indicating that local environmental factors influence the genetic structure of G. sylvestre, which may help in future cultivation and conservation efforts.
Article Abstract
Background: Gymnema sylvestre (Retz.) R. Br. ex Schult. is a well-known medicinal plant against diabetes in India. There is as such no organized cultivation in India, and the plant is still being collected from the wild for their therapeutic uses. It is, therefore, important to estimate the genetic diversity and population genetic structure of G. sylvestre to ascertain the genetically diverse germplasm. The present study, therefore, was undertaken to analyze the genetic variability in 118 accessions belonging to 11 wild populations of G. sylvestre using directed amplification of minisatellite-region DNA (DAMD) and inter simple sequence repeats (ISSR).
Results: The present genetic analyses of 11 populations with 25 markers (8 DAMD and 17 ISSR) revealed significant genetic diversity (H = 0.26, I = 0.40, PPL = 80.89%) at a species level, while the average genetic diversity at the population level was low. Among the 11 populations studied, PCH and UTK populations showed maximum genetic diversity, followed by KNR and AMB, while TEL population revealed the lowest genetic diversity. AMOVA and G values (0.18) revealed that most of the genetic variations are found within populations and very less among populations, and higher gene flow (N = 2.29) was found to be responsible for the genetic homogenization of the populations. The clustering pattern resulting from the UPGMA dendrogram was in congruence with STRUCTURE and PCoA, segregating all the 11 populations into two main genetic clusters: cluster I (populations of North and Central India) and cluster II (populations of South India). The clustering patterns obtained from all three statistical methods indicate that the genetic structure in G. sylvestre populations corresponds to the geographical diversity of the populations and represents a strong genetic structure.
Conclusion: The genetically diverse populations identified during the present study could be a potential genetic resource for further prospecting and conserving this important plant resource.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079795 | PMC |
| http://dx.doi.org/10.1186/s43141-023-00497-7 | DOI Listing |
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