Representation and learning of concepts are critical problems in data science and cognitive science. However, the existing research about concept learning has one prevalent disadvantage: incomplete and complex cognitive. Meanwhile, as a practical mathematical tool for concept representation and concept learning, two-way learning (2WL) also has some issues leading to the stagnation of its related research: the concept can only learn from specific information granules and lacks a concept evolution mechanism. To overcome these challenges, we propose the two-way concept-cognitive learning (TCCL) method for enhancing the flexibility and evolution ability of 2WL for concept learning. We first analyze the fundamental relationship between two-way granule concepts in the cognitive system to build a novel cognitive mechanism. Furthermore, the movement three-way decision (M-3WD) method is introduced to 2WL to study the concept evolution mechanism via the concept movement viewpoint. Unlike the existing 2WL method, the primary consideration of TCCL is two-way concept evolution rather than information granules transformation. Finally, to interpret and help understand TCCL, an example analysis and some experiments on various datasets are carried out to demonstrate our method's effectiveness. The results show that TCCL is more flexible and less time-consuming than 2WL, and meanwhile, TCCL can also learn the same concept as the latter method in concept learning. In addition, from the perspective of concept learning ability, TCCL is more generalization of concepts than the granule concept cognitive learning model (CCLM).
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http://dx.doi.org/10.1109/TNNLS.2023.3235800 | DOI Listing |
Mater Today Bio
February 2025
Department of Physical Chemistry and Materials Science, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3., H-1111, Budapest, Hungary.
Mucosal membranes with strong variability in their viscoelastic properties line numerous organs and are often targeted by mucoadhesive formulations, e.g., highly swellable hydroxypropylmethylcellulose (HPMC) and slightly cross-linked poly(acrylic acid) (PAA) tablets.
View Article and Find Full Text PDFPhys Chem Chem Phys
January 2025
Facultad de Ingeniería, Arquitectura y Diseño, Universidad San Sebastián, Bellavista 7, Santiago, 8420524, Chile.
The formation of [CuSnSb] serves as a template for heterometallic species to evaluate the resulting aromatic properties. Our results indicated that the spherical aromatic characteristics of the [CuSnSb] building unit remained in the overall aggregate, featuring an induced shielding cone from different orientations of the external field. Furthermore, the isostructural and isoelectronic [Sn] cluster sustained similar characteristics, which supported the notion of a direct relationship between [CuSnSb] and [Sn] cluster dimers.
View Article and Find Full Text PDFLakartidningen
January 2025
professor, universitetssjukhusöverläkare, Sahlgrenska universitetssjukhuset, Göteborg; Sahlgrenska akademin, Göteborgs universitet.
Several of the requirements for obtaining a medical degree according to the Swedish Higher Education Ordinance illustrate the scientific basis of the profession, and systematic reviews as well as health technology assessments (HTA) constitute cornerstones in evidence-based medicine. In this study, medical students' experience of scientific education related to the profession was explored, and their knowledge achieved was sampled by five multiple-choice questions (MCQ). A total of 433 out of 641 students attending the final semester in six medical schools in Sweden participated (response rate: 68%).
View Article and Find Full Text PDFGenome Med
January 2025
Blizard Institute, Barts and The London Faculty of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, UK.
Background: Senescence classification is an acknowledged challenge within the field, as markers are cell-type and context dependent. Currently, multiple morphological and immunofluorescence markers are required. However, emerging scRNA-seq datasets have enabled an increased understanding of senescent cell heterogeneity.
View Article and Find Full Text PDFCell Rep Med
January 2025
Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA. Electronic address:
Alpha-1 antitrypsin (AAT) deficiency (AATD) is a monogenic disease caused by misfolding of AAT variants resulting in gain-of-toxic aggregation in the liver and loss of monomer activity in the lung leading to chronic obstructive pulmonary disease (COPD). Using high-throughput screening, we discovered a bioactive natural product, phenethyl isothiocyanate (PEITC), highly enriched in cruciferous vegetables, including watercress and broccoli, which improves the level of monomer secretion and neutrophil elastase (NE) inhibitory activity of AAT-Z through the endoplasmic reticulum (ER) redox sensor protein disulfide isomerase (PDI) A4 (PDIA4). The intracellular polymer burden of AAT-Z can be managed by combination treatment of PEITC and an autophagy activator.
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