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Intrafraction motion analysis in online adaptive radiotherapy for esophageal cancer. | LitMetric

Intrafraction motion analysis in online adaptive radiotherapy for esophageal cancer.

Phys Imaging Radiat Oncol

Department of Radiation Oncology, University Medical Center Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.

Published: April 2023

AI Article Synopsis

Article Abstract

Intrafraction motion during magnetic resonance (MR)-guided dose delivery of esophageal cancer tumors was retrospectively analyzed. Deformable image registration of cine-MR series resulted in gross tumor volume motion profiles in all directions, which were subsequently filtered to isolate respiratory and drift motion. A large variability in intrafraction motion patterns was observed between patients. Median 95% peak-to-peak motion was 7.7 (3.7 - 18.3) mm, 2.1 (0.7 - 5.7) mm and 2.4 (0.5 - 5.6) mm in cranio-caudal, left-right and anterior-posterior directions, relatively. Furthermore, intrafraction drift was generally modest (<5mm). A patient specific approach could lead to very small margins (<3mm) for most patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068261PMC
http://dx.doi.org/10.1016/j.phro.2023.100432DOI Listing

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