High-dimensional small sample size data, which may lead to singularity in computation, are becoming increasingly common in the field of pattern recognition. Moreover, it is still an open problem how to extract the most suitable low-dimensional features for the support vector machine (SVM) and simultaneously avoid singularity so as to enhance the SVM's performance. To address these problems, this article designs a novel framework that integrates the discriminative feature extraction and sparse feature selection into the support vector framework to make full use of the classifiers' characteristics to find the optimal/maximal classification margin. As such, the extracted low-dimensional features from high-dimensional data are more suitable for SVM to obtain good performance. Thus, a novel algorithm, called the maximal margin SVM (MSVM), is proposed to achieve this goal. An alternatively iterative learning strategy is adopted in MSVM to learn the optimal discriminative sparse subspace and the corresponding support vectors. The mechanism and the essence of the designed MSVM are revealed. The computational complexity and convergence are also analyzed and validated. Experimental results on some well-known databases (including breastmnist, pneumoniamnist, colon-cancer, etc.) show the great potential of MSVM against classical discriminant analysis methods and SVM-related methods, and the codes can be available on https://www.scholat.com/laizhihui.
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http://dx.doi.org/10.1109/TCYB.2022.3232800 | DOI Listing |
Sci Rep
January 2025
Department of Orthopedics, Shanghai Changhai Hospital, Shanghai, 200433, China.
With the emergence of numerous classifications, surgical treatment for adolescent idiopathic scoliosis (AIS) can be guided more effectively. However, surgical decision-making and optimal strategies still lack standardization and personalized customization. Our study aims to devise proper deep learning (DL) models that incorporate key factors influencing surgical outcomes on the coronal plane in AIS patients to facilitate surgical decision-making and predict surgical results for AIS patients.
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January 2025
Gastroenterology Department, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
To retrospectively develop and validate an interpretable deep learning model and nomogram utilizing endoscopic ultrasound (EUS) images to predict pancreatic neuroendocrine tumors (PNETs). Following confirmation via pathological examination, a retrospective analysis was performed on a cohort of 266 patients, comprising 115 individuals diagnosed with PNETs and 151 with pancreatic cancer. These patients were randomly assigned to the training or test group in a 7:3 ratio.
View Article and Find Full Text PDFAcad Radiol
January 2025
Department of Radiology, Xinhua Hospital, Shanghai Jiaotong University Medical School, Shanghai 200092, China (Z.H.W., Y.Q.M., X.Y.W., N.X.Y., X.Y.W., G.R.). Electronic address:
Rationale And Objectives: The expression of human epidermal growth factor receptor 2 (HER2) in gastric cancer is closely associated with its treatment outcomes and prognosis. This study aims to develop and validate a HER2 prediction model based on computed tomography (CT). Additionally, the study evaluates the robustness of the proposed model.
View Article and Find Full Text PDFJMIR Res Protoc
January 2025
South African Medical Research Council/University of Johannesburg Pan African Centre for Epidemics Research Extramural Unit, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa.
Background: HIV testing is the cornerstone of HIV prevention and a pivotal step in realizing the Joint United Nations Program on HIV/AIDS (UNAIDS) goal of ending AIDS by 2030. Despite the availability of relevant survey data, there exists a research gap in using machine learning (ML) to analyze and predict HIV testing among adults in South Africa. Further investigation is needed to bridge this knowledge gap and inform evidence-based interventions to improve HIV testing.
View Article and Find Full Text PDFJ Control Release
January 2025
Department of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China. Electronic address:
The anti-inflammatory role of miR-23b-3p (miR-23b) is known in autoimmune diseases like multiple sclerosis, systemic lupus erythematosus, and rheumatoid arthritis. However, its role in sepsis-related acute lung injury (ALI) and its effect on macrophages in ALI remain unexplored. This investigation aimed to evaluate miR-23b's therapeutic potential in macrophages in the context of ALI.
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