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http://dx.doi.org/10.1093/asj/sjad091 | DOI Listing |
Brain Behav Immun
December 2024
Teaching and Experimental Center, Liaoning University of Traditional Chinese Medicine, Shenyang 110847, China. Electronic address:
Proc Natl Acad Sci U S A
December 2024
Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110.
Childhood exposure to social disadvantage is a major risk factor for psychiatric disorders and poor developmental, educational, and occupational outcomes, presumably because adverse exposures alter the neurodevelopmental processes that contribute to risk trajectories. Yet, given the limited social mobility in the United States and other countries, childhood social disadvantage is frequently preceded by maternal social disadvantage during pregnancy, potentially altering fetal brain development during a period of high neuroplasticity through hormonal, microbiome, epigenetic, and immune factors that cross the placenta and fetal blood-brain barrier. The current study examines prenatal social disadvantage to determine whether these exposures in utero are associated with alterations in functional brain networks as early as birth.
View Article and Find Full Text PDFFacial Plast Surg Aesthet Med
November 2024
Private practice, Uberlandia, Brazil.
Fluids Barriers CNS
September 2024
Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
For centuries, the meninges have been described as three membranes: the inner pia, middle arachnoid and outer dura. It was therefore sensational when in early 2023 Science magazine published a report of a previously unrecognized - 4th - meningeal membrane located between the pia and arachnoid. Multiple features were claimed for this new membrane: a single cell layer marked by the transcription factor Prox1 that formed a barrier to low molecular weight substances and separated the subarachnoid space (SAS) into two fluid-filled compartments, not one as previously described.
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