Objective: From October 1, 2018, the Northern Territory (NT) of Australia introduced a minimum unit price (MUP) for alcohol of AU$1.30 per standard drink. The MUP was introduced to address the high alcohol consumption rates and harms within the NT. This study aimed to investigate the unique short-term impact of the MUP on alcohol-related assaults across the NT, for the NT overall and separately for four key regions (Darwin and Palmerston, Alice Springs, Katherine, and Tennant Creek); which allowed for the consideration of differences in concurrent alcohol interventions and population (e.g., Alice Springs had Police Auxiliary Liquor Inspectors (PALIs) introduced on October 1, 2018, whereas Darwin and Palmerston only had the MUP introduced in this period). PALIs effectively equate to a police officer being stationed in every off-premise liquor vendor.
Method: Using data from January 2013 to September 2019, interrupted time series (ITS) analyses assessed the short-term impact of the MUP on the monthly rate of police-recorded alcohol-related assaults.
Results: A 14% reduction ( = -3.07 [-5.40, -0.74], < .010) was found for alcohol-related assault offenses per 10,000 in Darwin/Palmerston. Significant reductions were also noted in Alice Springs and the NT overall, although PALIs are likely to have contributed to these reductions in addition to the MUP.
Conclusions: This short-term impact warrants longer-term follow-up to determine whether the reductions in alcohol-related assaults following the introduction of MUP are maintained, and the extent to which assault rates are influenced by other alcohol-policy interventions in the NT.
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http://dx.doi.org/10.15288/jsad.22-00128 | DOI Listing |
BMC Public Health
January 2025
Key Laboratory of Cities Mitigation and Adaptation to Climate Change in Shanghai (CMACC), Shanghai, 200092, China.
Background: Due to climate change and rapid urbanization, the frequency of heatwave events in East China has increased considerably since the 21st century, which has a considerable influence on human health, such as heatstroke. However, few studies have been conducted in this region on the relationship between heatstroke and meteorological conditions. To address this point, this study aimed to analyze the characteristics of heatstroke and their relationship with meteorological conditions in Hefei, China.
View Article and Find Full Text PDFPublic Health
January 2025
Department of Public Health, Policy and Systems, University of Liverpool, UK. Electronic address:
Objectives: Alcohol consumption and its associated harms pose a significant challenge to public health in the UK. To address this issue, Wales implemented a Minimum Unit Price policy (MUP) in February 2020, setting a minimum price of 50p per UK unit of alcohol (10 ml/8 g). In this study we evaluate the policy's impact on alcohol sales metrics to gauge its effectiveness in improving public health outcomes.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210023, China.
The abrasion of melamine cleaning sponges release microplastic fibers (MPFs) into the environment, yet the potential risks remain unknown. Here, we evaluated the ingestion, elimination, and toxic effects of melamine MPFs on Daphnia magna through acute and chronic exposures. This new type of MPFs displayed different morphology (a combination of linear and branched fibers with a length ranging from 10 to 157 μm) from the widely-studied MPFs released from textiles (longer and thicker linear fibers but no branched fibers).
View Article and Find Full Text PDFCancer Metab
January 2025
Department of Dermatology, Venereology and Allergology, University Medical Center and Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, Mannheim, 68167, Germany.
Background: In malignant melanoma, liver metastases significantly reduce survival, even despite highly effective new therapies. Given the increase in metabolic liver diseases such as metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH), this study investigated the impact of liver sinusoidal endothelial cell (LSEC)-specific alterations in MASLD/MASH on hepatic melanoma metastasis.
Methods: Mice were fed a choline-deficient L-amino acid-defined (CDAA) diet for ten weeks to induce MASH-associated liver fibrosis, or a CDAA diet or a high fat diet (HFD) for shorter periods of time to induce early steatosis-associated alterations.
Sci Rep
January 2025
Department of Chemical Engineering, Al-Amarah University, Maysan, Iraq.
In this paper, the usage of a predictive surrogate model for the estimate of flow variables in the transient phase of coolant injection from the nose cone by combining the Long Short-Term Memory (LSTM) and Proper Orthogonal Decomposition (POD) technique. The velocity, pressure, and mass fraction of the counterflow jet is evaluated via this hybrid technique and the source of discrepancy of a predictive surrogate model with Full order model is explained in this study. The POD modes for the efficient prediction of the different flow variables are defined.
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