Objectives: Due to advancing digitalisation, it is of interest to develop standardised and reproducible fully automated analysis methods of cranial structures in order to reduce the workload in diagnosis and treatment planning and to generate objectifiable data. The aim of this study was to train and evaluate an algorithm based on deep learning methods for fully automated detection of craniofacial landmarks in cone-beam computed tomography (CBCT) in terms of accuracy, speed, and reproducibility.
Materials And Methods: A total of 931 CBCTs were used to train the algorithm. To test the algorithm, 35 landmarks were located manually by three experts and automatically by the algorithm in 114 CBCTs. The time and distance between the measured values and the ground truth previously determined by an orthodontist were analyzed. Intraindividual variations in manual localization of landmarks were determined using 50 CBCTs analyzed twice.
Results: The results showed no statistically significant difference between the two measurement methods. Overall, with a mean error of 2.73 mm, the AI was 2.12% better and 95% faster than the experts. In the area of bilateral cranial structures, the AI was able to achieve better results than the experts on average.
Conclusion: The achieved accuracy of automatic landmark detection was in a clinically acceptable range, is comparable in precision to manual landmark determination, and requires less time.
Clinical Relevance: Further enlargement of the database and continued development and optimization of the algorithm may lead to ubiquitous fully automated localization and analysis of CBCT datasets in future routine clinical practice.
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http://dx.doi.org/10.1007/s00784-023-04978-4 | DOI Listing |
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Convolutional neural networks (CNNs) have become indispensable to medical image diagnosis research, enabling the automated differentiation of diseased images from extensive medical image datasets. Due to their efficacy, these methods raise significant privacy concerns regarding patient images and diagnostic models. To address these issues, some researchers have explored privacy-preserving medical image diagnosis schemes using fully homomorphic encryption (FHE).
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December 2024
Surgical Pathology and Cytopathology Unit, Department of Medicine-DIMED, University of Padua School of Medicine, Padua, Italy.
Pathology laboratories are currently facing remarkable issues in the management of their archives due to the ongoing increase in the production of formalin-fixed paraffin-embedded (FFPE) blocks, which is often coupled with inadequate spatial and environmental storing conditions. The manual process of storage and retrieving further increases the likelihood of human-based mistakes, wastes professionals' working time, and, ultimately, widens reports signing turn-around times. In the present work, we outline the strategies underlying the development of an automated archive at the pathology services of the University of Modena.
View Article and Find Full Text PDFAlzheimers Dement
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Miin Wu School of Computing, National Cheng Kung University, Tainan, Taiwan.
Background: Alzheimer's disease (AD) has been associated with speech and language impairment. Recent progress in the field has led to the development of automated AD detection using audio-based methods, because it has a great potential for cross-linguistic detection. In this investigation, we utilised a pretrained deep learning model to automatically detect AD, leveraging acoustic data derived from Chinese speech.
View Article and Find Full Text PDFAlzheimers Dement
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Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Background: This study responds to the urgent need for automated and reliable methods to detect cognitive impairments on a large scale. It leverages natural language processing (NLP) techniques to predict dementia and mild cognitive impairment (MCI) using clinical notes from electronic health records (EHR).
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Sci Rep
January 2025
Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.
The last decades have brought an interest in ultrasound applications in dermatology. Especially in the case of atopic dermatitis, where the formation of a subepidermal low echogenic band (SLEB) may serve as an independent indicator of the effects of treatment, the use of ultrasound is of particular interest. This study proposes and evaluates the computer-aided diagnosis method for assessing atopic dermatitis (AD).
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