AI Article Synopsis
- Atrial fibrillation (AF) is more common in athletes, but the reasons behind it are still unclear.
- A study on Standardbred racehorses showed that trained horses sustained AF longer after induced tachypacing, but had no significant differences in atrial size or inflammation compared to untrained horses.
- Untrained horses exhibited greater complexity in AF between the atria, whereas trained horses did not show this difference, indicating varied mechanisms of AF in relation to athletic training.
Article Abstract
Atrial fibrillation (AF) is more prevalent in athletes, and currently, the mechanisms are not fully understood. Atrial fibrillation inducibility and stability was investigated in trained and untrained Standardbred racehorses. The horses underwent echocardiography for evaluation of atrial size. High-density mapping during AF was performed, and the presence of structural remodeling, as well as the expression of inflammatory and pro-inflammatory markers in the atria, was studied. Atrial fibrillation sustained significantly longer after tachypacing in the trained horses, whereas no difference in AF inducibility was found. The untrained horses displayed a significant difference in the AF complexity when comparing right and left atria, whereas such difference was not observed in the trained animals. No evidence of increased structural remodeling or inflammation could be identified. Left atrial dimensions were not significantly increased. The increased AF sustainability in trained horses was not related to fibrosis or inflammation as seen in other animal exercise models.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615936 | PMC |
| http://dx.doi.org/10.1007/s12265-023-10378-6 | DOI Listing |
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