AI Article Synopsis

  • Chronic wound infections are a major barrier to healing, particularly in diabetic foot syndrome, affecting up to 30% of patients.
  • Accurate diagnosis and proper microbiological testing are vital for effective treatment, with this study focusing on infected chronic wounds in Polish patients from 2013-2021.
  • The analysis of samples from 1,199 patients revealed that the most frequently isolated microorganisms included 14.3% MRSA and 2.4% VRE, highlighting the need for further research on drug susceptibility to enhance treatment recommendations.

Article Abstract

Chronic wound infection is one of the factors that hinder or prevent its healing. The incidence of infection may vary depending on the type of wound. It is estimated that clinically significant infection in diabetic foot syndrome occurs in up to 30% of patients. Accurate diagnosis of infection features and proper microbiological tests are crucial for introducing of appropriate local and often systemic treatment. The aim of the study was a comparative analysis of the microbiota found in infected chronic wounds in patients from Poland, consulted on an outpatient basis at a wound care center in 2013-2021. The indication for microbiology culture tests was the detection of local signs of infection, and sampling was preceded by appropriate wound debridement. The standard culture technique was a deep-tissue biopsy. Material for the study was collected from 1,199 patients. Overall, 3,917 results of microbiological tests were subjected to retrospective analysis. The paper presents the results in the form of the number of cultured microorganisms and their relative incidence as percentages, considering the division into the types of wounds from which the material was obtained. The most frequently isolated microorganisms in the analyzed group were (14.3% of this group were MRSA - methicillin-resistant ) and (2.4% of this group were VRE - vancomycin-resistant ). Further analysis of such an extensive database, especially regarding drug susceptibility of isolated microorganisms, seems crucial to elaborate new recommendations for empirical antibacterial treatment of infected chronic wounds.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266287PMC
http://dx.doi.org/10.33073/pjm-2023-014DOI Listing

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