New compartment model for COVID-19.

Sci Rep

Kyushu University, Fukuoka, 819-0395, Japan.

Published: April 2023

The SIR or susceptible-infected-recovered model is the standard compartment model for understanding epidemics and has been used all over the world for COVID-19. While the SIR model assumes that infected patients are identical to symptomatic and infectious patients, it is now known that in COVID-19 pre-symptomatic patients are infectious and there are significant number of asymptomatic patients who are infectious. In this paper, population is separated into five compartments for COVID-19; susceptible individuals (S), pre-symptomatic patients (P), asymptomatic patients (A), quarantined patients (Q) and recovered and/or dead patients (R). The time evolution of population in each compartment is described by a set of ordinary differential equations. Numerical solution to the set of differential equations shows that quarantining pre-symptomatic and asymptomatic patients is effective in controlling the pandemic.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068699PMC
http://dx.doi.org/10.1038/s41598-023-32159-6DOI Listing

Publication Analysis

Top Keywords

asymptomatic patients
12
patients
9
compartment model
8
covid-19 sir
8
pre-symptomatic patients
8
patients infectious
8
differential equations
8
covid-19
4
model covid-19
4
sir susceptible-infected-recovered
4

Similar Publications

Three cases of hemoglobin M disease in a family lineage: Case report and literature review.

Medicine (Baltimore)

January 2025

Department of Pediatric Hematology, Children's Medical Center, The First Hospital of Jilin University, Changchun, China.

Rationale: This study presents a case of hemoglobin M disease (HMD), a rare inherited disorder characterized by persistent cyanosis and hypoxemia, observed across 3 generations within a single family. The diagnosis of HMD poses significant challenges, particularly in asymptomatic individuals, due to its rarity and the subtlety of its symptoms. Notably, there is a scarcity of reports on methemoglobinemia in pediatric populations, which further complicates early detection and intervention.

View Article and Find Full Text PDF

Objective: Spinal fusion is a commonly performed surgical procedure used to relieve pain, deformity, and instability of various spinal pathologies. Although there have been attempts to standardize spinal fusion assessment radiologically, there is currently no unified definition that also considers clinical symptomology. This review attempts to create a more holistic and standardized definition of spinal fusion.

View Article and Find Full Text PDF

Evaluation of Awareness, Knowledge, Attitude and Practices Related to Toxoplasmosis Among Females in Algeria.

Vet Sci

December 2024

Laboratoire d'Exploration et Valorisation des Écosystèmes Steppiques, Faculty of Natural and Life Sciences, University of Djelfa, PO Box 3117, Djelfa 17000, Algeria.

Toxoplasmosis is a major veterinary and public health issue affecting humans and animals, where felids represent the definitive hosts of the causative agent . While the infections are mostly asymptomatic, the disease could be severe in immune-compromised patients and pregnant women. This study was conducted to evaluate the level of knowledge, practice, and attitude toward this disease among a sample of Algerian women.

View Article and Find Full Text PDF

Safety, Immunogenicity, and Efficacy of Cytomegalovirus Vaccines: A Systematic Review of Randomized Controlled Trials.

Vaccines (Basel)

January 2025

Department of Biomedical Sciences and Public Health, Section of Hygiene, Preventive Medicine and Public Health, Polytechnic University of the Marche Region, 60126 Ancona, Italy.

Cytomegalovirus (CMV) is widespread and mostly causes asymptomatic infections in immunocompetent hosts, but it may lead to severe and life-threatening diseases in immunocompromised individuals, such as transplant patients and congenitally infected children, representing a significant public health concern. Although there are no licensed CMV vaccines, the development of a CMV vaccine is considered a high priority due to its potential to reduce the burden associated with CMV-related complications, and several approaches are under investigation. The objective of this systematic review was to synthesize the evidence on various CMV vaccines currently under clinical development.

View Article and Find Full Text PDF

Description of the Serological Response After Treatment of Chronic Imported Schistosomiasis.

Trop Med Infect Dis

January 2025

National Reference Centre for Imported Tropical Diseases, Infectious Diseases Department, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.

Background: Chronic schistosomiasis can lead to significant morbidity. Serology is highly sensitive; however, its role in assessing treatment response is controversial. This study aimed to analyze serological values following treatment of chronic imported schistosomiasis.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!