Secondary feedstocks, such as food waste (FW), have been used for yeasts (e.g. Starmerella bombicola) to produce sophorolipids (SLs), which are commercially available biosurfactants. However, the quality of FW varies by location and season and may contains chemicals that inhibit SLs production. Therefore, it is crucial to identify such inhibitors and, if possible, remove them, to ensure efficient utilization. In this study, large scale FW was first analysed to determine the concentration of potential inhibitors. Lacticacid, acetic acid and ethanol were identified and found to be inhibitors of the growth of S. bombicola and its SLs production. Various methods were then evaluated for their ability to remove these inhibitors. Finally, a simple and effective strategy for removing inhibitors from FW was developed that complied with the 12 principles of green chemistry and could be adopted by industry for high SLs production.
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http://dx.doi.org/10.1016/j.biortech.2023.128993 | DOI Listing |
Biosci Biotechnol Biochem
December 2024
Laboratory of Plant Chemical Regulation, School of Agriculture, Meiji University. 1-1-1, Higashi-Mita, Tama-ku, Kawasaki, Kanagawa, Japan.
Strigolactones (SLs) are apocarotenoid plant hormones that regulate shoot branching. The natural SLs can be divided into two groups, canonical and non-canonical SLs according to those chemical structures. In a model plant, Arabidopsis thaliana, it has been thought to produce only non-canonical SLs.
View Article and Find Full Text PDFInt J Pharm
December 2024
Delta Pharmaceutics Ltd., Chatham, Kent ME4 4TB, UK; Centre for Research Innovation (CRI), University of Greenwich, Chatham ME4 4TB, UK. Electronic address:
In this study Selective Laser Sintering (SLS) was used to produce bilayer tablets containing rosuvastatin and acetylsalicylic acid. Initially, monolithic tablets of each drug were manufactured using different laser intensities in order to identify their impact on the tablet's dissolution, friability and hardness. After the optimization, the final bilayer tablet was fabricated using a new method, that allowed the printing using different powder blends.
View Article and Find Full Text PDFBioorg Chem
December 2024
Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China. Electronic address:
Sesquiterpene lactones (SLs) are a class of natural products with diverse structural scaffoldings and biological activities, making them intriguing objects in the fields of pharmaceutical industry, drug development, and pharmacology. Herein, fifteen SLs, including eleven undescribed SLs compounds sauruintones A-K (1-8 and 13-15), were isolated and identified from the aerial parts of Saussurea involucrata. Their structures were characterized by using mass spectrometry, spectroscopic methods, computational calculations, and single crystal X-ray diffraction.
View Article and Find Full Text PDFMaterials (Basel)
December 2024
School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
High-entropy alloys (HEAs) have drawn substantial attention on account of their outstanding properties. Additive manufacturing (AM), which has emerged as a successful approach for fabricating metallic materials, allows for the production of complex components based on three-dimensional (3D) computer-aided design (CAD) models. This paper reviews the advancements in the AM of HEAs, encompassing a variety of AM techniques, including selective laser melting (SLM), selective laser sintering (SLS), selective electron beam melting (SEBM), directed energy deposition (DED), binder jetting (BJT), direct ink writing (DIW), and additive friction stir deposition (AFSD).
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
College of Agronomy, Shandong Agricultural University, No. 61 Daizong Street, Tai'an, Shandong 271018, People's Republic of China. Electronic address:
Drought poses significant challenges to crop productivity, necessitating a deeper understanding of plant adaptive mechanisms. Strigolactones (SLs), a class of phytohormones, have been recognized as crucial regulators in plant responses to drought, yet the specific role of SL receptor in drought tolerance in cotton (Gossypium hirsutum L.) remains underexplored.
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