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Neurobiological mechanisms of antidepressant properties of psilocybin: A systematic review of blood biomarkers.
Prog Neuropsychopharmacol Biol Psychiatry
January 2025
Department of Psychiatry, University Medical Center Groningen, Groningen, the Netherlands.
Psilocybin represents a novel therapeutic approach for individuals with major depressive disorder (MDD) who do not respond to conventional antidepressant treatment. Investigating the influence of psilocybin on the pathophysiological processes involved in MDD could enhance our neurobiological understanding of the presumed antidepressant action mechanism. This systematic review aims to summarize the results of human studies investigating changes in blood-based biomarkers of MDD to guide future research on potentially relevant analytes that could be monitored in clinical trials.
View Article and Find Full Text PDFBackground: Prolonged discrimination is psychosocial stressor, influencing mortality rates and contributing to cardiovascular and mental health disorders among Black individuals. Allostatic load (AL), the wear and tear of stress is a biological cumulative risk that links psychosocial stressors to adverse health outcomes. Currently, a consolidate review of evidence underscoring discrimination and AL in Black individuals is not available.
View Article and Find Full Text PDFBackground: Primary progressive aphasia (PPA) is a currently incurable and relatively rare language-based neurodegenerative dementia syndrome, which negatively impacts communication and quality of life. Non-pharmacologic interventions show promise but have lacked randomized controlled trials (RCT). Here we report outcomes for Communication Bridge-2 (CB2), the first global telemedicine speech-language (RCT) for PPA.
View Article and Find Full Text PDFPsychological Distress in Patients With Asbestos-Related Diseases and Their Families: A Systematic Literature Review.
Psychooncology
January 2025
Department of Psychology, University of Turin, Turin, Italy.
Background: Exposure to asbestos in the workplace is currently recognized as one of the leading causes of work-related deaths, with more than half of deaths attributable to cancer.
Aims: The aim of this systematic literature review was to investigate the mental health and psychological distress of patients affected by asbestos-related diseases and their caregivers.
Methods: The review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses.
Purpose: Electronic flashcards (EFs) are a widely used learning resource in medical education. This scoping review provides a comprehensive overview of the existing empirical research on EFs and a direction for future research on EF interventions. The authors organized the reviewed articles into 4 nonmutually exclusive categories: development, delivery, utilization, and associated outcomes.
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