AI Article Synopsis
- - The study aimed to evaluate the effectiveness of using both optical and radio-guided techniques in identifying sentinel nodes in patients with oral squamous cell carcinoma located in the anterior oral cavity.
- - Researchers conducted a prospective study involving 50 patients, utilizing a tracer and a near-infrared camera to detect sentinel nodes during surgery, while tracking the accuracy of the identification process.
- - Results showed that all patients had detectable sentinel nodes, with 44% identified only through optical imaging; importantly, the false omission rate was 0%, indicating high reliability of the method.
Article Abstract
Purpose: The purpose was to investigate the diagnostic performance of bimodal optical and radio-guided sentinel node biopsy (SNB) for oral squamous cell carcinoma (OSCC) sub-sites in the anterior oral cavity.
Methods: Prospective study of 50 consecutive patients with cN0 OSCC scheduled for SNB was injected with the tracer complex Tc99m:ICG:Nacocoll. A near-infrared camera was applied for optical SN detection. Endpoints were modality for intraoperative SN detection and false omission rate at follow-up.
Results: In all patients, a SN could be detected. In 12/50 (24%) of cases, the SPECT/CT showed no focus in level 1, but intraoperatively a SN in level 1 was optically detected. In 22/50 cases (44%), an additional SN was identified only due to the optical imaging. At follow-up, the false omission rate was 0%.
Conclusion: Optical imaging appears to be an effective tool to allow real-time SN identification comprising level 1 unaffected by possible interference of radiation site from the injection.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219873 | PMC |
| http://dx.doi.org/10.1007/s00405-023-07939-5 | DOI Listing |
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