AI Article Synopsis
- * Common substances that can lead to this condition include hydroquinone and other phenolic compounds, which result in a distinctive "banana-shaped" pigment appearance under a microscope.
- * The authors discuss a rare case where chronic use of Teavigo, a supplement high in antioxidants, triggered exogenous ochronosis in areas such as the conjunctiva, sclera, and skin.
Article Abstract
Exogenous ochronosis refers to accumulation of homogentisic acid metabolites in tissues, manifesting as pigmentation of affected tissues. Phenolic compounds are most commonly implicated, including hydroquinone, quinine, phenol, resorcinol, mercury, and picric acid. The affected connective tissues exhibit brownish discoloration when heavily pigmented and the histopathological appearance is characteristic with "banana-shaped" ochre-colored pigment deposits. Herein, the authors describe a rare case of exogenous ochronosis involving the conjunctiva, sclera and skin, as a result of chronic use of Teavigo (94% epigallocatechin gallate), a polyphenol compound with postulated antioxidant and antiapoptotic activity.
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| http://dx.doi.org/10.1097/IOP.0000000000002395 | DOI Listing |
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