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Management of hepatocellular carcinoma from diagnosis in routine clinical practice. | LitMetric

Aim: To assess real-world management of patients diagnosed with hepatocellular carcinoma (HCC) within an integrated delivery network.

Materials & Methods: A retrospective cohort analysis of adults newly diagnosed with HCC from January 2014 to March 2019. Overall survival and treatment journey were assessed over the entire available follow-up period per patient.

Results: Of the 462 patients, 85% had ≥1 treatment. The 24-month overall survival rate (95% CI) from first treatment was 77% (72-82%). Majority of Child-Pugh class A (71%) and B (60%) patients received locoregional therapy first. Half (53.6%) of the patients with liver transplantation first were Child-Pugh class C patients. Sorafenib was the predominant systemic therapy.

Conclusion: This integrated delivery network data analysis offers a comprehensive insight into the real-world management of HCC.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064261PMC
http://dx.doi.org/10.2217/hep-2021-0011DOI Listing

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