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| http://dx.doi.org/10.1016/j.puhip.2023.100380 | DOI Listing |
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A comprehensive comparison of PARP inhibitors as maintenance therapy in platinum-sensitive recurrent ovarian cancer: a systematic review and network meta-analysis.
J Ovarian Res
January 2025
Department of Health Education, Nanjing Municipal Center for Disease Control and Prevention, No.3, Zizhulin Road, Nanjing, Jiangsu Province, 210003, China.
Background: PARP inhibitors (PARPis) have shown promising effectiveness for ovarian cancer. This network meta-analysis (PROSPERO registration number CRD42024503390) comprehensively evaluated the effectiveness and safety of PARPis in platinum-sensitive recurrent ovarian cancer (PSROC).
Methods: Articles published before January 6, 2024 were obtained from electronic databases.
Kidney immunology from pathophysiology to clinical translation.
Nat Rev Immunol
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III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Kidney diseases are widespread and represent a considerable medical, social and economic burden. However, there has been marked progress in understanding the immunological aspects of kidney disease. This includes the identification of distinct intrarenal immunological niches and characterization of kidney disease endotypes according to the underlying molecular immunopathology, as well as a better understanding of the pathological roles for T cells, mononuclear phagocytes and B cells and the renal elements they target.
View Article and Find Full Text PDFChronic kidney disease.
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Division of Nephrology, Department of Medicine IV, Hospital of the Ludwig-Maximilians University, Munich, Germany.
Chronic kidney disease (CKD) is defined by persistent abnormalities of kidney function or structure that have consequences for the health. A progressive decline of excretory kidney function has effects on body homeostasis. CKD is tightly associated with accelerated cardiovascular disease and severe infections, and with premature death.
View Article and Find Full Text PDFAllostatic load and psychological characteristics of transgender individuals. Preliminary case-control findings.
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First Department of Psychiatry, Eginition Hospital, National and Kapodistrian University of Athens, 72-74 Vas. Sophias Ave, Athens 11528, Greece.
Despite considerable social progress, transgender people still face multiple chronic stressors. This study evaluated the allostatic load index and assessed specific psychological characteristics between transgender and cisgender participants who were matched based on age and assigned-at-birth gender. Twenty-one transgender people (52.
View Article and Find Full Text PDFRe-architecture for requirements of academic space development in the universities: design and validitation of RASD questionnaire.
Sci Rep
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Department of Leadership and Educational management, Faculty of Psychology and Educational Sciences, Shahid Beheshti University, Tehran, Iran.
Universities are the cornerstone of social development and progress; however, it is essential to enhance the academic environment to support this mission. The objective of this research is to identify the Requirements for Academic Space Development (RASD) in universities. The present study was conducted in 2022-2023 using a mixed-method with a qualitative-quantitative sequence.
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